Avascular necrosis as a part of 'long COVID-19'

被引:68
作者
Agarwala, Sanjay R. [1 ]
Vijayvargiya, Mayank [2 ]
Pandey, Prashant [2 ]
机构
[1] PD Hinduja Natl Hosp, Orthopaed, Mumbai, Maharashtra, India
[2] PD Hinduja Natl Hosp & Med Res Ctr, Orthopaed, Mumbai, Maharashtra, India
关键词
COVID-19; musculoskeletal and joint disorders; unwanted effects; adverse reactions; groin pain; drugs; musculoskeletal and joint diseases; FEMORAL-HEAD; OSTEONECROSIS; PATHOGENESIS; THERAPY;
D O I
10.1136/bcr-2021-242101
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
'Long COVID-19' can affect different body systems. At present, avascular necrosis (AVN) as a sequalae of 'long COVID-19' has yet not been documented. By large-scale use of life-saving corticosteroids in COVID-19 cases, we anticipate that there will be a resurgence of AVN cases. We report a series of three cases in which patients developed AVN of the femoral head after being treated for COVID-19 infection. The mean dose of prednisolone used in these cases was 758 mg (400-1250 mg), which is less than the mean cumulative dose of around 2000 mg steroid, documented in the literature as causative for AVN. Patients were symptomatic and developed early AVN presentation at a mean of 58 days after COVID-19 diagnosis as compared with the literature which shows that it generally takes 6 months to 1 year to develop AVN post steroid exposure.
引用
收藏
页数:3
相关论文
共 13 条
[1]   The use of alendronate in the treatment of avascular necrosis of the femoral head FOLLOW-UP TO EIGHT YEARS [J].
Agarwala, S. ;
Shah, S. ;
Joshi, V. R. .
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 2009, 91B (08) :1013-1018
[2]   Bisphosphonate Combination Therapy in the Management of Postchemotherapy Avascular Necrosis of the Femoral Head in Adolescents and Young Adults: A Retrospective Study From India [J].
Agarwala, Sanjay ;
Banavali, Shripad D. ;
Vijayvargiya, Mayank .
JOURNAL OF GLOBAL ONCOLOGY, 2018, 4 :1-11
[3]   MULTIPLE JOINT OSTEONECROSIS FOLLOWING SHORT-TERM STEROID-THERAPY - CASE-REPORT [J].
ANDERTON, JM ;
HELM, R .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1982, 64 (01) :139-141
[4]  
Assouline-Dayan Y, 2002, SEMIN ARTHRITIS RHEU, V32, P94, DOI 10.1053/sarh.2002.33724
[5]  
Chan K L, 2012, Open Orthop J, V6, P449, DOI 10.2174/1874325001206010449
[6]   Renin-Angiotensin-Aldosterone System Inhibitors in COVID-19: A Review [J].
Ferrari, Filipe ;
Martins, Vitor Magnus ;
Fuchs, Flavio Danni ;
Stein, Ricardo .
CLINICS, 2021, 76
[7]   Hydroxychloroquine in the treatment of outpatients with mildly symptomatic COVID-19: a multi-center observational study [J].
Ip, Andrew ;
Ahn, Jaeil ;
Zhou, Yizhao ;
Goy, Andre H. ;
Hansen, Eric ;
Pecora, Andrew L. ;
Sinclaire, Brittany A. ;
Bednarz, Urszula ;
Marafelias, Michael ;
Sawczuk, Ihor S. ;
Underwood, Joseph P., III ;
Walker, David M. ;
Prasad, Rajiv ;
Sweeney, Robert L. ;
Ponce, Marie G. ;
La Capra, Samuel ;
Cunningham, Frank J. ;
Calise, Arthur G. ;
Pulver, Bradley L. ;
Ruocco, Dominic ;
Mojares, Greggory E. ;
Eagan, Michael P. ;
Ziontz, Kristy L. ;
Mastrokyriakos, Paul ;
Goldberg, Stuart L. .
BMC INFECTIOUS DISEASES, 2021, 21 (01)
[8]  
Jones JP, 2001, ARTHRITIS ALLIED CON, P2143
[9]   Short- and potential long-term adverse health outcomes of COVID-19: a rapid review [J].
Leung, T. Y. M. ;
Chan, A. Y. L. ;
Chan, E. W. ;
Chan, V. K. Y. ;
Chui, C. S. L. ;
Cowling, B. J. ;
Gao, L. ;
Ge, M. Q. ;
Hung, I. F. N. ;
Ip, M. S. M. ;
Ip, P. ;
Lau, K. K. ;
Lau, C. S. ;
Lau, L. K. W. ;
Leung, W. K. ;
Li, X. ;
Luo, H. ;
Man, K. K. C. ;
Ng, V. W. S. ;
Siu, C. W. ;
Wan, E. Y. F. ;
Wing, Y. K. ;
Wong, C. S. M. ;
Wong, K. H. T. ;
Wong, I. C. K. .
EMERGING MICROBES & INFECTIONS, 2020, 9 (01) :2190-2199
[10]   Covid-19: What do we know about "long covid"? [J].
Mahase, Elisabeth .
BMJ-BRITISH MEDICAL JOURNAL, 2020, 370