Atrial fibrillation in Brugada syndrome: Current perspectives

被引：26

作者：

Vlachos, Konstantinos ^{[1
,2
]}

Mascia, Giuseppe ^{[3
]}

Martin, Claire A. ^{[1
,2
,4
]}

Bazoukis, George ^{[5
]}

Frontera, Antonio ^{[1
,2
]}

Cheniti, Ghassen ^{[1
,2
]}

Letsas, Konstantinos P. ^{[5
]}

Efremidis, Micheal ^{[5
]}

Georgopoulos, Stamatis ^{[5
]}

Gkalapis, Charis ^{[6
,7
]}

Duchateau, Josselin ^{[1
,2
]}

Parmbrun, Thomas ^{[1
,2
]}

Derval, Nicholas ^{[1
,2
]}

Hocini, Meleze ^{[1
,2
]}

Haissaguerre, Michel ^{[1
,2
]}

Jais, Pierre ^{[1
,2
]}

Sacher, Frederic ^{[1
,2
]}

机构：

[1] CHU Bordeaux, Hop Cardiol Haut Leveque, Pessac, France

[2] IHU LIRYC, Pessac, France

[3] Azienda USL Toscana, Cardiol & Electrophysiol Unit, Florence, Italy

[4] Royal Papworth Hosp, Dept Electrophysiol Cardiol, Cambridge, England

[5] Gen Hosp Athens Evangelismos, Dept Cardiol 2, Lab Electrophysiol, Athens, Greece

[6] Klinikum Vest, Dept Electrophysiol Cardiol, Recklinghausen, Germany

[7] Ruhr Univ Bochum, Akad Lehrkrankenhaus, Dept Cardiol, Bochum, Germany

来源：

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY | 2020年 / 31卷 / 04期

关键词：

arrhythmia mechanism; atrial fibrillation; Brugada syndrome; genetics; IMPLANTABLE CARDIOVERTER-DEFIBRILLATOR; SUDDEN CARDIAC DEATH; PULMONARY VEIN ISOLATION; ST-SEGMENT ELEVATION; HIGH-RISK; SUPRAVENTRICULAR TACHYARRHYTHMIAS; CATHETER ABLATION; PREVALENCE; MANAGEMENT; SYNCOPE;

D O I：

10.1111/jce.14361

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The incidence of atrial fibrillation (AF) in Brugada syndrome (BrS) has been reported at between 9% and 53% by different series, but the true prevalence is unknown. However, AF may be the presenting feature in some patients. The underlying mechanisms for AF may be a combination of multiple factors, genetic or acquired, that may impact upon autonomic function, atrial structure, and conduction velocities or other unknown factors. The presence of AF has been associated with a more malignant course, with a greater incidence of syncope and ventricular arrhythmias, thus acting as marker of more advanced disease. Regarding the management of patients with AF, antiarrhythmic drugs effective in preventing malignant arrhythmias in BrS such as quinidine or invasive treatment with pulmonary vein isolation (PVI) may be useful in AF treatment. In this review, we aim to present the current perspectives regarding the genetics, pathophysiology, management, and prognosis of AF in patients with BrS.

引用

页码：975 / 984

页数：10

共 85 条

[51] Epicardial substrate ablation for Brugada syndrome [J].

Nademanee, Koonlawee ;

Hocini, Meleze ;

Haissaguerre, Michel .

HEART RHYTHM, 2017, 14 (03) :457-461

[52] Fibrosis, Connexin-43, and Conduction Abnormalities in the Brugada Syndrome [J].

Nademanee, Koonlawee ;

Raju, Hariharan ;

de Noronha, Sofia V. ;

Papadakis, Michael ;

Robinson, Laurence ;

Rothery, Stephen ;

Makita, Naomasa ;

Kowase, Shinya ;

Boonmee, Nakorn ;

Vitayakritsirikul, Vorapot ;

Ratanarapee, Samrerng ;

Sharma, Sanjay ;

van der Wal, Allard C. ;

Christiansen, Michael ;

Tan, Hanno L. ;

Wilde, Arthur A. ;

Nogami, Akihiko ;

Sheppard, Mary N. ;

Veerakul, Gumpanart ;

Behr, Elijah R. .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2015, 66 (18) :1976-1986

[53] Prevention of Ventricular Fibrillation Episodes in Brugada Syndrome by Catheter Ablation Over the Anterior Right Ventricular Outflow Tract Epicardium [J].

Nademanee, Koonlawee ;

Veerakul, Gumpanart ;

Chandanamattha, Pakorn ;

Chaothawee, Lertlak ;

Ariyachaipanich, Aekarach ;

Jirasirirojanakorn, Kriengkrai ;

Likittanasombat, Khanchit ;

Bhuripanyo, Kiertijai ;

Ngarmukos, Tachapong .

CIRCULATION, 2011, 123 (12) :1270-U38

[54] Atrial Remodeling and Atrial Fibrillation Mechanisms and Implications [J].

Nattel, Stanley ;

Burstein, Brett ;

Dobrev, Dobromir .

CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 2008, 1 (01) :62-73

[55] SCN1Bb R214Q found in 3 patients: 1 with Brugada syndrome and 2 with lone atrial fibrillation [J].

Olesen, Morten S. ;

Holst, Anders G. ;

Svendsen, Jesper Hastrup ;

Haunso, Stig ;

Tfelt-Hansen, Jacob .

HEART RHYTHM, 2012, 9 (05) :770-773

[56] Electrical Substrate Elimination in 135 Consecutive Patients With Brugada Syndrome [J].

Pappone, Carlo ;

Brugada, Josep ;

Vicedomini, Gabriele ;

Ciconte, Giuseppe ;

Manguso, Francesco ;

Saviano, Massimo ;

Vitale, Raffaele ;

Cuko, Amarild ;

Giannelli, Luigi ;

Calovic, Zarko ;

Conti, Manuel ;

Pozzi, Paolo ;

Natalizia, Andrea ;

Crisa, Simonetta ;

Borrelli, Valeria ;

Brugada, Ramon ;

Sarquella-Brugada, Georgia ;

Guazzi, Marco ;

Frigiola, Alessandro ;

Menicanti, Lorenzo ;

Santinelli, Vincenzo .

CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 2017, 10 (05)

[57] New-onset atrial fibrillation as first clinical manifestation of latent Brugada syndrome: prevalence and clinical significance [J].

Pappone, Carlo ;

Radinovic, Andrea ;

Manguso, Francesco ;

Vicedomini, Gabriele ;

Sala, Simone ;

Sacco, Francesco Maria ;

Ciconte, Giuseppe ;

Saviano, Massimo ;

Ferrari, Maurizio ;

Sommariva, Elena ;

Sacchi, Stefania ;

Ciaccio, Cristiano ;

Kallergis, Eleftherios M. ;

Santinelli, Vincenzo .

EUROPEAN HEART JOURNAL, 2009, 30 (24) :2985-2992

[58] Clinical characteristics of Brugada syndrome in a Korean population [J].

Park, DW ;

Nam, GB ;

Rhee, KS ;

Han, GH ;

Choi, KJ ;

Kim, YH .

CIRCULATION JOURNAL, 2003, 67 (11) :934-939

[59] SNPs Identified as Modulators of ECG Traits in the General Population Do Not Markedly Affect ECG Traits during Acute Myocardial Infarction nor Ventricular Fibrillation Risk in This Condition [J].

Pazoki, Raha ;

de Jong, Jonas S. S. G. ;

Marsman, Roos F. ;

Bruinsma, Nienke ;

Dekker, Lukas R. C. ;

Wilde, Arthur A. M. ;

Bezzina, Connie R. ;

Tanck, Michael W. T. .

PLOS ONE, 2013, 8 (02)

[60] Genome-wide association study of PR interval [J].

Pfeufer, Arne ;

van Noord, Charlotte ;

Marciante, Kristin D. ;

Arking, Dan E. ;

Larson, Martin G. ;

Smith, Albert Vernon ;

Tarasov, Kirill V. ;

Mueller, Martina ;

Sotoodehnia, Nona ;

Sinner, Moritz F. ;

Verwoert, Germaine C. ;

Li, Man ;

Kao, W. H. Linda ;

Koettgen, Anna ;

Coresh, Josef ;

Bis, Joshua C. ;

Psaty, Bruce M. ;

Rice, Kenneth ;

Rotter, Jerome I. ;

Rivadeneira, Fernando ;

Hofman, Albert ;

Kors, Jan A. ;

Stricker, Bruno H. C. ;

Uitterlinden, Andre G. ;

van Duijn, Cornelia M. ;

Beckmann, Britt M. ;

Sauter, Wiebke ;

Gieger, Christian ;

Lubitz, Steven A. ;

Newton-Cheh, Christopher ;

Wang, Thomas J. ;

Magnani, Jared W. ;

Schnabel, Renate B. ;

Chung, Mina K. ;

Barnard, John ;

Smith, Jonathan D. ;

Van Wagoner, David R. ;

Vasan, Ramachandran S. ;

Aspelund, Thor ;

Eiriksdottir, Gudny ;

Harris, Tamara B. ;

Launer, Lenore J. ;

Najjar, Samer S. ;

Lakatta, Edward ;

Schlessinger, David ;

Uda, Manuela ;

Abecasis, Goncalo R. ;

Mueller-Myhsok, Bertram ;

Ehret, Georg B. ;

Boerwinkle, Eric .

NATURE GENETICS, 2010, 42 (02) :153-U89

← 1 2 3 4 5 6 7 8 9 →