Medication and Falls: Risk and Optimization

被引：56

作者：

Boyle, Nichola ^{[1
,2
,3
]}

Naganathan, Vasi ^{[1
,2
,3
]}

Cumming, Robert G. ^{[1
,4
]}

机构：

[1] Concord Repatriat Gen Hosp, Ctr Educ & Res Ageing, Concord, NSW 2139, Australia

[2] Univ Sydney, Concord Clin Sch, Sydney Med Sch, Sydney, NSW 2006, Australia

[3] Concord Repatriat Gen Hosp, Dept Geriatr Med, Concord, NSW 2139, Australia

[4] Univ Sydney, Sydney Sch Publ Hlth, Sydney, NSW 2006, Australia

来源：

CLINICS IN GERIATRIC MEDICINE | 2010年 / 26卷 / 04期

关键词：

Medication; Falls; Older people; Polypharmacy; SYSTEM-ACTIVE MEDICATIONS; ADVERSE DRUG EVENTS; LONG-TERM-CARE; HIP BONE LOSS; OLDER-PEOPLE; THIAZIDE DIURETICS; INCREASING DRUGS; INJURIOUS FALLS; ELDERLY-PEOPLE; RECURRENT FALLS;

D O I：

10.1016/j.cger.2010.06.007

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

The association between drugs and falls has been widely studied in the past 3 decades with increasingly robust evidence of a causal link Both specific classes of drugs and the total number of drugs taken are associated with falls This review examines some of the reasons why older people are at greater risk of drug-related adverse events such as falls We discuss the role of drugs in general and polypharmacy (the concurrent use of multiple drugs) on the risk of falling with a focus on community-dwelling older people We critically appraise the evidence that specific classes of drugs such as benzodiazepines and antidepressants increase the risk of falling and that falls can be prevented through interventions that target medications

引用

页码：583 / +

页数：24

共 116 条

[1] Influence of age and gender on risperidone plasma concentrations [J].