Effectiveness and Safety of Treatment with Neodymium:YAG Laser 1064 nm in Patients with Classic and Epidemic Kaposi Sarcoma

被引：5

作者：

Silvestri, Martina ^{[1
]}

Latini, Alessandra ^{[2
]}

La Parola, Ilaria Lesnoni ^{[2
]}

Messina, Claudia ^{[2
]}

Nistico, Steven Paul ^{[1
]}

Cameli, Norma ^{[2
]}

机构：

[1] Magna Graecia Univ Catanzaro, Dept Hlth Sci, Unit Dermatol, I-88100 Catanzaro, Italy

[2] San Gallicano Dermatol Inst IRCCS, Dept Dermatol, I-00144 Rome, Italy

来源：

BIOENGINEERING-BASEL | 2022年 / 9卷 / 03期

关键词：

YAG; classic Kaposi's sarcoma; HIV; laser treatment;

D O I：

10.3390/bioengineering9030106

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Kaposi's sarcoma (KS) is a vascular neoplasm Herpes Virus 8 (HHV8), which can affect the skin, mucous membranes and viscera. There is currently no standard treatment for KS; this study evaluated the efficacy and safety of Neodymium:YAG (Nd:YAG) laser 1064 nm treatment in patients with classic and HIV-associated KS. 15 patients with classic KS (group A) and 15 with epidemic KS (group B), with exclusively cutaneous localization, were treated with Nd:YAG laser 1064 nm. Four treatment sessions were performed at 4 weeks intervals. 24/30 (80%) of treated patients underwent clinical improvement. Better results have been obtained in HIV-positive patients, especially in terms of reduced lesion size and the flattening of elevated lesions. The 1064 nm Nd:YAG laser is effective and safe in the treatment of classic and epidemic KS, especially in patients with symptomatic, slow-progressing local disease, where other treatment options may be inappropriate.

引用

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