Selective Mg Insertion into Substituted Mono- and Dichloro Arenes in the Presence of LiCl: A New Preparation of Boscalid

被引：10

作者：

Dunst, Cora ^{[1
]}

Knochel, Paul ^{[1
]}

机构：

[1] Univ Munich, Dept Chem, D-81377 Munich, Germany

来源：

SYNLETT | 2011年 / 14期

基金：

欧洲研究理事会;

关键词：

insertion; magnesium; lithium; aryl chlorides; boscalid; HIGHLY REACTIVE METALS; ORGANOZINC REAGENTS; ORGANOMETALLIC REAGENTS; CROSS-COUPLINGS; PALLADIUM; MAGNESIUM; HALIDES; ARYLMAGNESIUM; CHLORIDES; CATALYST;

D O I：

10.1055/s-0030-1261168

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The LiCl-mediated Mg insertion into polysubstituted aryl chlorides bearing up to three chloro substituents in ortho or meta position selectively leads to Grignard reagents which readily react with various electrophiles. As an application, we have developed a new formal synthesis of boscalid.

引用

收藏

页码：2064 / 2068

页数：5

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