Multilayer soft lithography of perfluoropolyether based elastomer for microfluidic device fabrication

被引：37

作者：

Devaraju, Naga Sai Gopi Krishna ^{[1
]}

Unger, Marc Alexander ^{[1
]}

机构：

[1] Fluidigm Corp, San Francisco, CA USA

来源：

LAB ON A CHIP | 2011年 / 11卷 / 11期

关键词：

INTEGRATION; SYSTEMS; VALVES;

D O I：

10.1039/c0lc00274g

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The compatibility of microfluidic devices with solvents and other chemicals is extremely important for many applications such as organic synthesis in microreactors and drug screening. We report the successful fabrication of microfluidic devices from a novel perfluoropolyether based polymer utilizing the Multilayer Soft Lithography (TM) (MSL) technique with simple, straightforward processing. The perfluorinated polymer SIFEL X-71 8115 is a highly chemically resistant elastomeric material. We demonstrate fabrication of a microfluidic device using an off-ratio bonding technique to bond multiple SIFEL layers, each patterned lithographically. The mechanical properties of the SIFEL MSL valves (including actuation pressures) are similar to PDMS MSL valves of the same geometry. Chemical compatibility tests highlight SIFEL's remarkable resistance to organic solvents, acids and alkalis.

引用

收藏

页码：1962 / 1967

页数：6

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