Identification, determination, and biological evaluation of a novel styrene trimer contained in polystyrene food containers. 2

被引：10

作者：

Hirano, S ^{[1
]}

Tanaka, M ^{[1
]}

Date, K ^{[1
]}

Ohno, K ^{[1
]}

Kobayashi, K ^{[1
]}

Sakurai, T ^{[1
]}

Nagao, Y ^{[1
]}

Nobuhara, Y ^{[1
]}

Yamada, T ^{[1
]}

机构：

[1] Nissin Food Prod Co Ltd, Cent Res Inst, Kusatsu, Shiga 5250055, Japan

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2001年 / 49卷 / 08期

关键词：

styrene trimer; tricyclo[6,2,2,0(2.7)]dodeca-2,9-diene; polystyrene; GC-MS (SIM) analysis; material and migration tests; biological evaluation;

D O I：

10.1021/jf010163m

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

An unidentified styrene trimer (ST) isolated from the acetonitrile extract of polystyrene (PS) food containers was characterized as (1S*,6R*,7S*,8S*,11R*)-6,11-diphenyltricyclo[6,2,2,0(2,7)]dodeca-2,9-diene. The content and migration of this compound in PS food containers were determined by GCMS (SIM). Furthermore, an endocrine-disrupting effect was tested using in vitro and in vivo assays of the compound. In conclusion, it seems that the compound does not present the effect.

引用

页码：4127 / 4131

页数：5

共 12 条

[1] Comparison of short-term estrogenicity tests for identification of hormone-disrupting chemicals [J].

Andersen, HR ;

Andersson, AM ;

Arnold, SF ;

Autrup, H ;

Barfoed, M ;

Beresford, NA ;

Bjerregaard, P ;

Christiansen, LB ;

Gissel, B ;

Hummel, R ;

Jorgensen, EB ;

Korsgaard, B ;

Le Guevel, R ;

Leffers, H ;

McLachlan, J ;

Moller, A ;

Nielsen, JB ;

Olea, N ;

Oles-Karasko, A ;

Pakdel, F ;

Pedersen, KL ;

Perez, P ;

Skakkeboek, NE ;

Sonnenschein, C ;

Soto, AM ;

Sumpter, JP ;

Thorpe, SM ;

Grandjean, P .

ENVIRONMENTAL HEALTH PERSPECTIVES, 1999, 107 :89-108

[2] Biological evaluation of styrene oligomers for endocrine-disrupting effects (II) [J].

Azuma, Y ;

Nobuhara, Y ;

Date, K ;

Ohno, K ;

Tanaka, K ;

Hirano, S ;

Kobayashi, K ;

Sakurai, T ;

Chiba, M ;

Yamada, T .

JOURNAL OF THE FOOD HYGIENIC SOCIETY OF JAPAN, 2000, 41 (02) :109-115

[3]

Colborn T., 1996, OUR STOLEN FUTURE, P253

[4]

Kawamura Y, 1998, J FOOD HYG SOC JPN, V39, P110

[5]

Kawamura Y, 1997, J FOOD HYG SOC JPN, V38, P307

[6]

KURZE J, 1970, ANGEW MAKROMOL CHEM, V12, P25

[7]

ODUM J, 1997, REGULATORY TOXICOLOG, V25, P175

[8]

SOTO AM, 1995, ENVIRON HEALTH PERSP, V103, P113, DOI 10.1289/ehp.95103s7113

[9]

SOTO AM, 1991, ENVIRON HEALTH PERSP, V92, P167, DOI 10.2307/3431154

[10]

*US EPA, 1998, END DISR SCREEN TEST

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