Modulation of host cell signal transduction pathways by Helicobacter pylori infection

被引:4
作者
Ceponis, PJM
Jones, NL
机构
[1] Hosp Sick Children, Res Inst, Toronto, ON M5G 1X8, Canada
[2] Univ Toronto, Dept Lab Med & Pathobiol, Toronto, ON, Canada
[3] Univ Toronto, Dept Paediat, Toronto, ON, Canada
关键词
epithelium; H pylori; signal transduction;
D O I
10.1155/2005/731817
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Bacterial pathogens modulate host cell signal transduction responses to establish infection and cause disease. The purpose of the present summary, first presented at the Canadian Helicobacter Study Group meeting, is to discuss current knowledge of specific Helicobacter pylori factors, including the vacuolating cytotoxin, cytotoxin-associated gene A and the type four secretion system encoded by the cytotoxin-associated gene pathogenicity island and review the host cell signal transduction cascades that they modulate.
引用
收藏
页码:415 / 420
页数:6
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