Deep Ulcers in the Ileum Associated with Mycophenolate Mofetil

被引：7

作者：

Sonoda, Akira ^{[1
]}

Wada, Kurato ^{[1
]}

Mizukami, Kazuhiro ^{[1
]}

Fukuda, Kensuke ^{[1
]}

Shuto, Mitsutaka ^{[1
]}

Okamoto, Kazuhisa ^{[1
]}

Ogawa, Ryo ^{[1
]}

Okimoto, Tadayoshi ^{[1
]}

Murakami, Kazunari ^{[1
]}

机构：

[1] Oita Univ, Dept Gastroenterol, Oita, Japan

来源：

INTERNAL MEDICINE | 2017年 / 56卷 / 21期

关键词：

mycophenolate mofetil; gastrointestinal toxicity; ileal ulcer; renal transplantation; TRANSPLANT RECIPIENTS; ENTEROCOLITIS; COLITIS; ACID;

D O I：

10.2169/internalmedicine.8815-17

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 54-year-old man was treated with mycophenolate mofetil (MMF) after undergoing living donor renal transplantation. Two years later, he experienced repeated episodes of diarrhea, and his C-reactive protein (CRP) level was found to be 12.63 mg/dL. Ileocolonoscopy showed multiple deep, punched-out ulcers that were similar to Beh double dagger et's disease (BD) and cytomegalovirus (CMV) in the ileum. CMV infection was suspected. However, anti-cytomegalovirus agents were ineffective. The patient was subsequently diagnosed with gastrointestinal toxicity of MMF and MMF was switched to mizoribine. His symptoms improved immediately, and his CRP level normalized. Six months later, the patient's mucosa was healed.

引用

页码：2883 / 2886

页数：4

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