Transoral laser microsurgery for laryngeal carcinoma: Survival analysis in a hospital-based population

被引:35
作者
Breda, Eduardo [1 ]
Catarino, Raquel [2 ]
Monteiro, Eurico [1 ]
机构
[1] Portuguese Inst Oncol Dr Francisco Gentil, Dept Otolaryngol, Oporto, Portugal
[2] Portuguese Inst Oncol Dr Francisco Gentil, Dept Mol Oncol GRP CI, Oporto, Portugal
来源
HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK | 2015年 / 37卷 / 08期
关键词
transoral laser microsurgery; supraglottic laryngeal carcinoma oncologic result; glottic laryngeal carcinoma oncologic result; functional outcome; organ preservation; SQUAMOUS-CELL CARCINOMA; SELECTIVE NECK DISSECTION; CARBON-DIOXIDE LASER; SUPRAGLOTTIC CARCINOMA; ADJUVANT RADIOTHERAPY; ORGAN PRESERVATION; GLOTTIC CANCER; UNITED-STATES; FOLLOW-UP; SURGERY;
D O I
10.1002/hed.23728
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
BackgroundAlthough already established for treatment for early-stage laryngeal cancers, transoral laser microsurgery indications for more advanced tumors are not unanimous. Additionally, no outcomes concerning the Portuguese population are currently accessible. MethodsOutcomes of 248 patients presenting laryngeal carcinoma primarily treated by transoral laser microsurgery with curative intention in tertiary referral center were retrospectively evaluated and compared with concerning literature. ResultsFor supraglottic tumors (23 stage I-II and 20 stage III-IV), 5-year disease-specific survival (DSS) was, respectively, 88.4% and 72.7%, and the total larynx-preservation rate was 90.7%. For glottic cancer (165 stage I-II and 40 stage III-IV), 5-year DSS was, respectively, 96.5% and 90.8% and the larynx preservation rate was 88.3%. ConclusionTransoral laser microsurgery, alone or with neck dissection and adjuvant therapy, is an efficient procedure for treatment of laryngeal cancer in different stages. To the best of our knowledge, this is the first study reporting transoral laser microsurgery outcomes in the Portuguese population. (c) 2014 Wiley Periodicals, Inc. Head Neck37: 1181-1186, 2015
引用
收藏
页码:1181 / 1186
页数:6
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