LIPOIC ACID PHARMACOKINETICS AT BASELINE AND 1 YEAR IN SECONDARY PROGRESSIVE MS

被引:12
作者
Bittner, Frank [1 ,2 ]
Murchison, Charles [1 ,2 ]
Koop, Dennis [2 ]
Bourdette, Dennis [1 ,2 ]
Spain, Rebecca [1 ,2 ]
机构
[1] VA Portland Hlth Care Syst, Portland, OR 97239 USA
[2] Oregon Hlth & Sci Univ, Portland, OR 97201 USA
基金
美国国家卫生研究院;
关键词
METABOLISM;
D O I
10.1212/NXI.0000000000000380
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
引用
收藏
页数:3
相关论文
共 6 条
[1]   Dose-proportionality of oral thioctic acid -: coincidence of assessments via pooled plasma and individual data [J].
Breithaupt-Grögler, K ;
Niebch, G ;
Schneider, E ;
Erb, K ;
Hermann, R ;
Blume, HH ;
Schug, BS ;
Belz, GG .
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 1999, 8 (01) :57-65
[2]   Enantiomer-selective pharmacokinetics, oral bioavailability, and sex effects of various alpha-lipoic acid dosage forms [J].
Hermann, Robert ;
Mungo, Julius ;
Cnota, Peter Juergen ;
Ziegler, Dan .
CLINICAL PHARMACOLOGY-ADVANCES AND APPLICATIONS, 2014, 6 :195-204
[3]   Pharmacokinetics and drug metabolism in the elderly [J].
Klotz, Ulrich .
DRUG METABOLISM REVIEWS, 2009, 41 (02) :67-76
[4]   Investigation of the drug-drug interaction between α-lipoic acid and valproate via mitochondrial β-oxidation [J].
Phua, Lee Cheng ;
New, Lee Sun ;
Goh, Catherine W. ;
Neo, Aveline H. ;
Browne, Edward R. ;
Chan, Eric C. Y. .
PHARMACEUTICAL RESEARCH, 2008, 25 (11) :2639-2649
[5]   Plasma kinetics, metabolism, and urinary excretion of alpha-lipoic acid following oral administration in healthy volunteers [J].
Teichert, J ;
Hermann, R ;
Ruus, P ;
Preiss, R .
JOURNAL OF CLINICAL PHARMACOLOGY, 2003, 43 (11) :1257-1267
[6]   Pharmacokinetic study of lipoic acid in multiple sclerosis: comparing mice and human pharmacokinetic parameters [J].
Yadav, Vijayshree ;
Marracci, Gail H. ;
Munar, Myrna Y. ;
Cherala, Ganesh ;
Stuber, Lauren E. ;
Alvarez, Lilia ;
Shinto, Lynne ;
Koop, Dennis R. ;
Bourdette, Dennis N. .
MULTIPLE SCLEROSIS JOURNAL, 2010, 16 (04) :387-397