Infectious Disease Transmission in Solid Organ Transplantation: Donor Evaluation, Recipient Risk, and Outcomes of Transmission

被引：63

作者：

White, Sarah L. ^{[1
]}

Rawlinson, William ^{[2
,3
]}

Boan, Peter ^{[4
,5
,6
]}

Sheppeard, Vicky ^{[7
]}

Wong, Germaine ^{[8
,9
,10
]}

Waller, Karen ^{[1
]}

Opdam, Helen ^{[11
,12
]}

Kaldor, John ^{[13
]}

Fink, Michael ^{[11
,14
]}

Verran, Deborah ^{[15
]}

Webster, Angela ^{[8
,10
]}

Wyburn, Kate ^{[1
,16
]}

Grayson, Lindsay ^{[11
,14
]}

Glanville, Allan ^{[17
]}

Cross, Nick ^{[18
]}

Irish, Ashley ^{[19
,20
]}

Coates, Toby ^{[21
,22
]}

Griffin, Anthony ^{[23
]}

Snell, Greg ^{[24
]}

Alexander, Stephen I. ^{[9
]}

Campbell, Scott ^{[25
]}

Chadban, Steven ^{[1
,16
]}

Macdonald, Peter ^{[26
,27
]}

Manley, Paul ^{[28
]}

Mehakovic, Eva ^{[12
]}

Ramachandran, Vidya ^{[2
]}

Mitchell, Alicia ^{[17
,29
,30
]}

Ison, Michael ^{[31
,32
]}

机构：

[1] Univ Sydney, Sydney Med Sch, Cent Clin Sch, Sydney, NSW, Australia

[2] Prince Wales Hosp, Serol & Virol Div, NSW Hlth Pathol, Sydney, NSW, Australia

[3] Univ New South Wales, Womens & Childrens Hlth & Biotechnol & Biomol Sci, Sch Med, Sydney, NSW, Australia

[4] Fiona Stanley Hosp, Dept Infect Dis, Perth, WA, Australia

[5] Fiona Stanley Hosp, Dept Microbiol, Perth, WA, Australia

[6] PathWest Lab Med, Perth, WA, Australia

[7] New South Wales Hlth, Communicable Dis Network Australia, Sydney, NSW, Australia

[8] Westmead Hosp, Ctr Transplant & Renal Res, Sydney, NSW, Australia

[9] Childrens Hosp Westmead, Ctr Kidney Res, Sydney, NSW, Australia

[10] Univ Sydney, Sydney Sch Publ Hlth, Sydney, NSW, Australia

[11] Austin Hlth, Melbourne, Australia

[12] Australian Govt, Organ & Tissue Author, Canberra, ACT, Australia

[13] Univ New South Wales, Kirby Inst, Sydney, NSW, Australia

[14] Univ Melbourne, Melbourne Med Sch, Dept Surg, Melbourne, Australia

[15] Royal Prince Alfred Hosp, Transplantat Serv, Sydney, NSW, Australia

[16] Royal Prince Alfred Hosp, Renal Med, Sydney, NSW, Australia

[17] St Vincents Hosp, Dept Thorac Med & Lung Transplantat, Sydney, NSW, Australia

[18] Christchurch Hosp, Canterbury Dist Hlth Board, Dept Nephrol, Christchurch, New Zealand

[19] Fiona Stanley Hosp, Dept Nephrol, Perth, WA, Australia

[20] Univ Western Australia, UWA Med Sch, Fac Hlth & Med Sci, Crawley, Australia

[21] Royal Adelaide Hosp, Renal & Transplantat, Adelaide, SA, Australia

[22] Univ Adelaide, Fac Hlth & Med Sci, Adelaide, SA, Australia

[23] Princess Alexandra Hosp, Renal Transplantat, Woolloongabba, Qld, Australia

[24] Alfred Hlth, Lung Transplant, Melbourne, Vic, Australia

[25] Univ Queensland, Princess Alexandra Hosp, Dept Renal Med, Woolloongabba, Qld, Australia

[26] St Vincents Hosp, Dept Cardiol, Sydney, NSW, Australia

[27] Univ New South Wales, St Vincents Hosp, Victor Chang Cardiac Res Inst, Sydney, NSW, Australia

[28] Auckland City Hosp, Auckland Dist Hlth Board, Kidney Disorders, Auckland, New Zealand

[29] Woolcock Inst Med Res, Sydney, NSW, Australia

[30] Univ Technol, Sch Med & Mol Biosci, Sydney, NSW, Australia

[31] Northwestern Univ, Feinberg Sch Med, Div Infect Dis, Chicago, IL 60611 USA

[32] Northwestern Univ, Feinberg Sch Med, Div Organ Transplantat, Chicago, IL 60611 USA

来源：

TRANSPLANTATION DIRECT | 2019年 / 5卷 / 01期

关键词：

HEPATITIS-C VIRUS; WEST-NILE-VIRUS; HUMAN-IMMUNODEFICIENCY-VIRUS; CELL LYMPHOTROPIC VIRUS; PROGRAM ANNUAL-REPORT; STRONGYLOIDES-STERCORALIS INFECTION; ANTIBODY-POSITIVE DONORS; MYCOBACTERIUM-TUBERCULOSIS INFECTION; ORTHOTOPIC LIVER-TRANSPLANTATION; MULTIDRUG-RESISTANT TUBERCULOSIS;

D O I：

10.1097/TXD.0000000000000852

中图分类号：

R3 [基础医学]; R4 [临床医学];

学科分类号：

1001 ; 1002 ; 100602 ;

摘要：

In 2016, the Transplantation Society of Australia and New Zealand, with the support of the Australian Government Organ and Tissue authority, commissioned a literature review on the topic of infectious disease transmission from deceased donors to recipients of solid organ transplants. The purpose of this review was to synthesize evidence on transmission risks, diagnostic test characteristics, and recipient management to inform best-practice clinical guidelines. The final review, presented as a special supplement in Transplantation Direct, collates case reports of transmission events and other peer-reviewed literature, and summarizes current (as of June 2017) international guidelines on donor screening and recipient management. Of particular interest at the time of writing was how to maximize utilization of donors at increased risk for transmission of human immunodeficiency virus, hepatitis C virus, and hepatitis B virus, given the recent developments, including the availability of direct-acting antivirals for hepatitis C virus and improvements in donor screening technologies. The review also covers emerging risks associated with recent epidemics (eg, Zika virus) and the risk of transmission of nonendemic pathogens related to donor travel history or country of origin. Lastly, the implications for recipient consent of expanded utilization of donors at increased risk of blood-borne viral disease transmission are considered.

引用

页数：91

共 462 条

[11]

[Anonymous], GUID MICR SAF HUM OR

[12]

[Anonymous], EURO SURVEILL

[13]

[Anonymous], AM J TRANSPLANT

[14]

[Anonymous], HIV UK2016 REPORT

[15]

[Anonymous], 2017 ANZOD ANN REP

[16]

[Anonymous], 2017, AUSTR DRUG TREND SER

[17]

[Anonymous], 2016, CLIN GUID ORG TRANSP

[18]

[Anonymous], HEPATOL RES

[19]

[Anonymous], 1988, TOXOPLASMOSIS ANIMAL

[20]

[Anonymous], 2015, SEXUALLY TRANSMITTED

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