Electrochemiluminescence aptasensor of TiO2/CdS:Mn hybrids for ultrasensitive detection of cytochrome c

被引：17
作者：
Bin, Na [1 ]
Li, Weili [1 ]
Yin, Xuehua [1 ]
Huang, Xiaohua [1 ]
Cai, Qingyun [1 ]
机构：
[1] Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, Peoples R China
来源：
TALANTA | 2016年 / 160卷
基金：
中国国家自然科学基金;
关键词：
Electrochemiluminescence aptasensor; Cytochrome c; Titanium dioxide nanowires; CdS:Mn quantum dots; SENSITIZED SOLAR-CELLS; TIO2 NANOWIRE ARRAYS; LITHIUM-ION BATTERIES; CDSE QUANTUM DOTS; SEMICONDUCTOR NANOCRYSTALS; CAPILLARY-ELECTROPHORESIS; MASS-SPECTROMETRY; H2O2; GENERATION; GRAPHENE OXIDE; COMPOSITE;
D O I：
10.1016/j.talanta.2016.07.046
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A novel electrochemiluminescence (ECL) aptasensor was proposed for ultrasensitive detection of cytochrome c (cyt c) using CdS:Mn quantum dot-modified TiO2 nanowires (NWs) as electrode. The Mn-doped CdS was deposited on the TiO2 NWs by successive ion layer adsorption and reaction (SILAR) as ECL emitter, on which thiol-modified aptamer of cyt c was attached via Cd-S bond. Due to the high photoelectrical transfer efficiency, the as-prepared aptasensor shows high selectivity and sensitivity towards cyt c with a detection limit of 9.5 fM and a linear range from 50 fM to 125 pM. (C) 2016 Elsevier B.V. All rights reserved.
引用
收藏
页码：570 / 576
页数：7
相关论文
共 52 条
[1]   H2O2 generation in Saccharomyces cerevisiae respiratory pet mutants:: Effect of cytochrome c [J].
Barros, MH ;
Netto, LES ;
Kowaltowski, AJ .
FREE RADICAL BIOLOGY AND MEDICINE, 2003, 35 (02) :179-188
[2]   Mn2+-Doped CdSe Quantum Dots: New Inorganic Materials for Spin-Electronics and Spin-Photonics [J].
Beaulac, Remi ;
Archer, Paul I. ;
Ochsenbein, Stefan T. ;
Gamelin, Daniel R. .
ADVANCED FUNCTIONAL MATERIALS, 2008, 18 (24) :3873-3891
[3]   The Apaf-1 apoptosome: a large caspase-activating complex [J].
Cain, K ;
Bratton, SB ;
Cohen, GM .
BIOCHIMIE, 2002, 84 (2-3) :203-214
[4]   Method for monitoring of mitochondrial cytochrome c release during cell death: Immunodetection of cytochrome c by flow cytometry after selective permeabilization of the plasma membrane [J].
Campos, Claudia B. L. ;
Paim, Bruno A. ;
Cosso, Ricardo G. ;
Castilho, Roger F. ;
Rottenberg, Hagai ;
Vercesi, Anibal E. .
CYTOMETRY PART A, 2006, 69A (06) :515-523
[5]   Selective fluorometry of cytochrome c using glutathione-capped CdTe quantum dots in weakly basic medium [J].
Cao, Ming ;
Cao, Chun ;
Liu, Meigui ;
Wang, Peng ;
Zhu, Changqing .
MICROCHIMICA ACTA, 2009, 165 (3-4) :341-346
[6]   Branched TiO2 Nanorods for Photoelectrochemical Hydrogen Production [J].
Cho, In Sun ;
Chen, Zhebo ;
Forman, Arnold J. ;
Kim, Dong Rip ;
Rao, Pratap M. ;
Jaramillo, Thomas F. ;
Zheng, Xiaolin .
NANO LETTERS, 2011, 11 (11) :4978-4984
[7]   Quantitation of cytochrome c release from rat liver mitochondria [J].
Crouser, ED ;
Gadd, ME ;
Julian, MW ;
Huff, JE ;
Broekemeier, KM ;
Robbins, KA ;
Pfeiffer, DR .
ANALYTICAL BIOCHEMISTRY, 2003, 317 (01) :67-75
[8]   Aptamer-functionalized solid phase microextraction-liquid chromatography/tandem mass spectrometry for selective enrichment and determination of thrombin [J].
Du, Fuyou ;
Alam, Md Nazmul ;
Pawliszyn, Janusz .
ANALYTICA CHIMICA ACTA, 2014, 845 :45-52
[9]   INVITRO SELECTION OF RNA MOLECULES THAT BIND SPECIFIC LIGANDS [J].
ELLINGTON, AD ;
SZOSTAK, JW .
NATURE, 1990, 346 (6287) :818-822
[10]   Redox reactions of heme-containing metalloproteins:: dynamic effects of self-assembled monolayers on thermodynamics and kinetics of cytochrome c electron-transfer reactions [J].
Fedurco, M .
COORDINATION CHEMISTRY REVIEWS, 2000, 209 :263-331
123456