Laser-assisted bioprinting to deal with tissue complexity in regenerative medicine

被引:52
作者
Guillemot, Fabien [1 ]
Guillotin, Bertrand [1 ]
Fontaine, Aurelien [1 ]
Ali, Muhammad [1 ]
Catros, Sylvain [1 ]
Keriquel, Virginie [1 ]
Fricain, Jean-Christophe [1 ]
Remy, Murielle [1 ]
Bareille, Reine [1 ]
Amedee-Vilamitjana, Joelle [1 ]
机构
[1] Univ Bordeaux Segalen, INSERM, Bordeaux, France
关键词
BETA-TITANIUM ALLOYS; CELLS; DESIGN; FABRICATION; MICROARRAYS; ELASTICITY; PARAMETERS; DEPOSITION; MATRICES; GROWTH;
D O I
10.1557/mrs.2011.272
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Laser-assisted bioprinting is one among several technologies that are being developed in the recent and growing field of bioprinting. Bioprinting is defined as the use of computer-aided transfer processes for patterning and assembling living and non-living materials with a prescribed 2D or 3D organization in order to produce bio-engineered structures serving in regenerative medicine, pharmacology, and basic cell biology studies. We describe the physical parameters that need to be tuned for laser-assisted bioprinting of materials and cells, with high throughput and controlled printing resolution. We present its applications for printing cells and tissue-relevant biomaterials, both in vitro and in vivo. Finally, we discuss how this technique may help in reproducing the local cell micro-environment and dealing with tissue complexity and heterogeneity for fabricating functional tissue-engineered 3D constructs.
引用
收藏
页码:1015 / 1019
页数:5
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