Emerging Severe and Fatal Infections Due to Klebsiella pneumoniae in Two University Hospitals in France

被引：146

作者：

Decre, Dominique ^{[1
]}

Verdet, Charlotte ^{[2
]}

Emirian, Aurelie ^{[1
]}

Le Gourrierec, Thibault ^{[3
]}

Petit, Jean-Claude ^{[1
]}

Offenstadt, Georges ^{[4
]}

Maury, Eric ^{[4
]}

Brisse, Sylvain ^{[5
]}

Arlet, Guillaume ^{[2
]}

机构：

[1] Hop St Antoine, Assistance Publ Hop Paris, Microbiol Lab, F-75012 Paris, France

[2] Hop Tenon, Assistance Publ Hop Paris, Bacteriol Lab, F-75970 Paris, France

[3] Hop Tenon, Assistance Publ Hop Paris, Serv Accueil Urgences, F-75970 Paris, France

[4] Hop St Antoine, Assistance Publ Hop Paris, Serv Reanimat Med, F-75012 Paris, France

[5] Inst Pasteur Genotypage Pathogenes & Sante Publ, Paris, France

来源：

JOURNAL OF CLINICAL MICROBIOLOGY | 2011年 / 49卷 / 08期

关键词：

PYOGENIC LIVER-ABSCESS; SEROTYPE K1; ASSOCIATION; BACTEREMIA; TAIWAN; RMPA; K2; GENES; MAGA;

D O I：

10.1128/JCM.00676-11

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Severe infections caused by hypermucoviscous Klebsiella pneumoniae have been reported in Southeast Asian countries over the past several decades. This report shows their emergence in France, with 12 cases observed during a 2-year period in two university hospitals. Two clones (sequence type 86 [ST86] and ST380) of serotype K2 caused five rapidly fatal bacteremia cases, three of which were associated with pneumonia, whereas seven liver abscess cases were caused by K1 strains of ST23.

引用

页码：3012 / 3014

页数：3

共 19 条

[1] Virulent Clones of Klebsiella pneumoniae: Identification and Evolutionary Scenario Based on Genomic and Phenotypic Characterization [J].

Brisse, Sylvain ;

Fevre, Cindy ;

Passet, Virginie ;

Issenhuth-Jeanjean, Sylvie ;

Tournebize, Regis ;

Diancourt, Laure ;

Grimont, Patrick .

PLOS ONE, 2009, 4 (03)

[2] Sequencing and analysis of the large virulence plasmid pLVPK of Klebsiella pneumoniae CG43 [J].

Chen, YT ;

Chang, HY ;

Lai, YC ;

Pan, CC ;

Tsai, SF ;

Peng, HL .

GENE, 2004, 337 :189-198

[3]

CHENG D-L, 1991, Archives of Internal Medicine, V151, P1557, DOI 10.1001/archinte.151.8.1557

[4]

Cheng Hsiao-Pei, 2002, Journal of Microbiology Immunology and Infection, V35, P85

[5] Isolation of a chromosomal region of Klebsiella pneumoniae associated with allantoin metabolism and liver infection [J].

Chou, HC ;

Lee, CZ ;

Ma, LC ;

Fang, CT ;

Chang, SC ;

Wang, JT .

INFECTION AND IMMUNITY, 2004, 72 (07) :3783-3792

[6]

Chuang HC, 2009, J MICROBIOL IMMUNOL, V42, P385

[7] A novel virulence gene in Klebsiella pneumoniae strains causing primary liver abscess and septic metastatic complications [J].

Fang, CT ;

Chuang, YP ;

Shun, CT ;

Chang, SC ;

Wang, JT .

JOURNAL OF EXPERIMENTAL MEDICINE, 2004, 199 (05) :697-705

[8] Invasive Infection With Hypermucoviscous Klebsiella pneumoniae: Multiple Cases Presenting to a Single Emergency Department in the United States [J].

Frazee, Bradley W. ;

Hansen, Shandi ;

Lambert, Larry .

ANNALS OF EMERGENCY MEDICINE, 2009, 53 (05) :639-642

[9] Community-acquired Klebsiella pneumoniae bacteremia:: Global differences in clinical patterns [J].

Ko, WC ;

Paterson, DL ;

Sagnimeni, AJ ;

Hansen, DS ;

Von Gottberg, A ;

Mohapatra, S ;

Casellas, JM ;

Goossens, H ;

Mulazimoglu, L ;

Trenholme, G ;

Klugman, KP ;

McCormack, JG ;

Yu, VL .

EMERGING INFECTIOUS DISEASES, 2002, 8 (02) :160-166

[10] Clinical implications of hypermucoviscosity phenotype in Klebsiella pneumoniae isolates:: association with invasive syndrome in patients with community-acquired bacteraemia [J].

Lee, H. -C. ;

Chuang, Y. -C. ;

Yu, W. -L. ;

Lee, N. -Y. ;

Chang, C. -M. ;

Ko, N. -Y. ;

Wang, L. -R. ;

Ko, W. -C. .

JOURNAL OF INTERNAL MEDICINE, 2006, 259 (06) :606-614

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