Fluorescence spectral properties of indocyanine green on a roughened platinum electrode: Metal-enhanced fluorescence

被引:13
作者
Geddes, CD
Parfenov, A
Roll, D
Uddin, MJ
Lakowicz, JR
机构
[1] Univ Maryland, Sch Med, Ctr Fluorescence Spect, Dept Biochem & Mol Biol, Baltimore, MD 21201 USA
[2] Univ Maryland, Inst Biotechnol, Ctr Med Biotechnol, Inst Fluorescence, Baltimore, MD 21201 USA
[3] Univ Maryland, Inst Biotechnol, Ctr Med Biotechnol, Ctr Fluorescence Spect, Baltimore, MD 21201 USA
关键词
roughened platinum electrode; metal-enhanced fluorescence; radiative decay engineering; indocyanine green;
D O I
10.1023/B:JOFL.0000008055.22336.0b
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The interactions of fluorophores with noble metal particles can modify their emission spectral properties, a relatively new phenomenon in fluorescence. We subsequently examined indocyanine green ( ICG), which is widely used in medical testing and imaging, in close proximity to an electrically roughened platinum electrode. The emission intensity and lifetimes were decreased about 2- fold on the roughened surface as compared to a smooth Pt surface, and the photostability about the same. Platinum does not appear promising for metal enhanced fluorescence, at least for long wavelength fluorophores.
引用
收藏
页码:453 / 457
页数:5
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