Speedy eye movements in multiple sclerosis: Association with performance on visual and nonvisual cognitive tests

被引:9
作者
Roberg, Brandon L. [1 ]
Bruce, Jared M. [1 ]
Feaster, H. Todd [2 ]
O'Bryan, Sean R. [1 ]
Westervelt, Holly J. [3 ,4 ]
Glusman, Morgan [1 ]
机构
[1] Univ Missouri, Dept Psychol, Kansas City, MO 64110 USA
[2] MidAmer Neurosci Inst, Lenexa, KS USA
[3] Brown Univ, Dept Psychiat & Human Behav, Alpert Med Sch, Providence, RI 02912 USA
[4] Rhode Isl Hosp, Dept Psychiat, Providence, RI USA
关键词
Multiple sclerosis; Ocular movements; Visual acuity; Neuropsychology; Cognition; ORAL TRAIL; IMPAIRMENT; ACUITY; ATTENTION;
D O I
10.1080/13803395.2014.983465
中图分类号
B849 [应用心理学];
学科分类号
040203 ;
摘要
Objective: Eye movement difficulties in multiple sclerosis (MS) are common and may influence performance on cognitive tests. The following studies examined associations between a new measure of speedy eye movement speed and visual/nonvisual cognitive tests. Method: In Experiment 1, MS patients (N = 71) were administered cognitive tests and the Speedy Eyes Test (SET) as a measure of purposeful speedy eye movements under timed conditions. Experiment 2 was composed of MS patients (n = 60) and a neurologically healthy comparison group (n = 31) and examined group differences in an abbreviated version of the SET. Results: In both studies, slower eye movements were significantly associated with poorer performance on cognitive tests with a large effect size in Experiment 1 and a medium effect size in Experiment 2. Analyses in Experiment 2 also revealed significant group differences in an abbreviated measure of the SET, where MS patients had slower eye movements than the comparison group. Conclusions: Pending further research, the SET, a brief, inexpensive, and nontechnical measure of speedy eye movement, may serve as a visual/oculomotor indicator of cognitive impairment in multiple sclerosis.
引用
收藏
页码:1 / 15
页数:15
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