Calcium-independent calcineurin regulation

被引:12
|
作者
Parry, RV [1 ]
June, CH
机构
[1] Univ Penn, Abramson Family Canc Res Inst, Philadelphia, PA 19104 USA
[2] Univ Penn, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA
关键词
D O I
10.1038/ni0903-821
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Calcineurin is negatively regulated by calcipressin 1. Analysis of calcipressin-deficient mice shows that survival of T helper type 1 cells is dependent on calcipressin, demonstrating another function for the regulation of calcineurin activity in T cells.
引用
收藏
页码:821 / 823
页数:3
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