Theoretical and experimental study of folic acid conjugated silver nanoparticles through electrostatic interaction for enhance antibacterial activity

被引：34

作者：

Chowdhuri, Angshuman Ray ^{[1
]}

Tripathy, Satyajit ^{[2
]}

Haldar, Chanchal ^{[1
]}

Chandra, Soumen ^{[1
]}

Das, Balaram ^{[2
]}

Roy, Somenath ^{[2
]}

Sahu, Sumanta Kumar ^{[1
]}

机构：

[1] Indian Sch Mines, Dept Appl Chem, Dhanbad 826004, Jharkhand, India

[2] Vidyasagar Univ, Dept Human Physiol Community Hlth, Immunol & Microbiol Lab, Midnapore 721102, India

来源：

RSC ADVANCES | 2015年 / 5卷 / 28期

关键词：

TARGETED DELIVERY; COMPLEXES; BACTERIA; CHITOSAN; SYSTEM; SHELL;

D O I：

10.1039/c4ra16785f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this paper, folic acid conjugated silver nanoparticles (Ag NPs) are developed for enhancing antibacterial activity. Here triethylamine is used as a capping agent as well as reducing agent during the synthesis of silver nanoparticles. Folic acid is conjugated on the surface of the functionalized silver nanoparticles through electrostatic interaction. The folic acid conjugated silver nanoparticles are characterized in terms of size and morphology by transmission electron microscopy (TEM) and field emission scanning electron microscopy (FESEM) respectively. The phase formation and surface functional groups of nanoparticles are analyzed by X-ray diffraction (XRD) and Fourier transform infrared (FTIR) spectroscopy respectively. Minimum inhibitory concentration study, minimum bactericidal concentration, growth pattern analysis and fluorescence carbon dot tagged nanoparticles uptake study reveal that the folic acid conjugated silver nanoparticles show good prospects against both Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacteria.

引用

页码：21515 / 21524

页数：10

共 40 条

[1] Antibacterial activity of SiO2/hydroxypropyl cellulose hybrid materials containing silver nanoparticles [J].

Angelova, Tsvetelina ;

Rangelova, Nadezhda ;

Yuryev, Ruslan ;

Georgieva, Nelly ;

Mueller, Rudolf .

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2012, 32 (05) :1241-1246

[2]

[Anonymous], 1971, ACTA PATHOL MIC SC

[3]

[Anonymous], 2005, INTERNET ELECT J MOL

[4] Co-selection of antibiotic and metal resistance [J].

Baker-Austin, C ;

Wright, MS ;

Stepanauskas, R ;

McArthur, JV .

TRENDS IN MICROBIOLOGY, 2006, 14 (04) :176-182

[5]

Chakraborty Subhankari Prasad, 2011, Asian Pacific Journal of Tropical Biomedicine, V1, P102, DOI 10.1016/S2221-1691(11)60005-1

[6] Nanoconjugated vancomycin: new opportunities for the development of anti-VRSA agents [J].

Chakraborty, Subhankari Prasad ;

Sahu, Sumanta Kumar ;

Mahapatra, Santanu Kar ;

Santra, Susmita ;

Bal, Manjusri ;

Roy, Somenath ;

Pramanik, Panchanan .

NANOTECHNOLOGY, 2010, 21 (10)

[7] pH-Responsive Mechanism of a Deoxycholic Acid and Folate Comodified Chitosan Micelle under Cancerous Environment [J].

Chen, Daiqin ;

Song, Peng ;

Jiang, Feng ;

Meng, Xiangyue ;

Sui, Weiping ;

Shu, Chunying ;

Wan, Li-Jun .

JOURNAL OF PHYSICAL CHEMISTRY B, 2013, 117 (05) :1261-1268

[8] Multifunctional Nanoplatforms for Targeted Multidrug-Resistant-Bacteria Theranostic Applications [J].

Dai, Xuemei ;

Fan, Zhen ;

Lu, Yuefeng ;

Ray, Paresh Chandra .

ACS APPLIED MATERIALS & INTERFACES, 2013, 5 (21) :11348-11354

[9] Antimicrobial activity of the metals and metal oxide nanoparticles [J].

Dizaj, Solmaz Maleki ;

Lotfipour, Farzaneh ;

Barzegar-Jalali, Mohammad ;

Zarrintan, Mohammad Hossein ;

Adibkia, Khosro .

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2014, 44 :278-284

[10]

Frisch A., 2007, REFERENCE VERSION 5

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