UPPER LIMB FUNCTION IN ADULTS WITH DUCHENNE MUSCULAR DYSTROPHY

被引:61
作者
Bartels, Bart [1 ,2 ]
Pangalila, Robert F. [1 ,2 ]
Bergen, Michael P. [2 ]
Cobben, Nicolle A. M. [3 ]
Stam, Henk J. [1 ]
Roebroeck, Marij E. [1 ]
机构
[1] Erasmus MC, Dept Rehabil Med, Rotterdam, Netherlands
[2] Rijndam Rehabil Ctr, Rotterdam, Netherlands
[3] Univ Hosp, Ctr Home Ventilat, Maastricht, Netherlands
关键词
Duchenne muscular dystrophy; adults; upper limb function; Motor Function Measure; muscle strength; range of motion; MOTOR FUNCTION; HAND; STRENGTH; SURVIVAL; POWER;
D O I
10.2340/16501977-0841
中图分类号
R49 [康复医学];
学科分类号
100215 ;
摘要
Objective: To determine upper limb function and associated factors in adults with Duchenne muscular dystrophy. Design: Cross-sectional study. Subjects: A sample of 70 men with Duchenne muscular dystrophy (age range 20-43 years). Methods: General motor function and, in particular, upper limb distal motor function, were assessed with the Motor Function Measure. Muscle strength and range of motion of the upper limb were evaluated using hand-held dynamometry, manual muscle-testing and goniometry. Associations were studied using Spearman's correlation coefficients and multiple linear regression analysis. Results: General motor function was severely impaired. Wide variability was found in distal motor function, muscle strength and range of motion of the upper limb, especially in early adulthood. Muscle strength and range of motion explained 76% of the variance in upper limb distal motor function. Conclusion: This study illustrates a large variability in upper limb function in adult patients with Duchenne muscular dystrophy, and identifies muscle strength and range of motion as factors strongly associated with upper limb function. These results suggest that preserving muscle strength and range of motion in Duchenne patients might be relevant for a better outcome of distal motor function of the upper limb when adult.
引用
收藏
页码:770 / 775
页数:6
相关论文
共 50 条
[41]   Two-Year Longitudinal Changes in Lower Limb Strength and Its Relation to Loss in Function in a Large Cohort of Patients With Duchenne Muscular Dystrophy [J].
Batra, Abhinandan ;
Harrington, Ann ;
Lott, Donovan J. ;
Willcocks, Rebecca ;
Senesac, Claudia R. ;
McGehee, William ;
Xu, Dandan ;
Mathur, Sunita ;
Daniels, Michael J. ;
Rooney, William D. ;
Forbes, Sean C. ;
Triplett, William ;
Deol, Jasjit K. ;
Arpan, Ishu ;
Bendixen, Roxanne ;
Finkel, Richard ;
Finanger, Erika ;
Tennekoon, Gihan ;
Byrne, Barry ;
Russman, Barry ;
Sweeney, H. Lee ;
Walter, Glenn ;
Vandenborne, Krista .
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION, 2018, 97 (10) :734-740
[42]   THE IMPACT OF NUTRITION ON RESPIRATORY FUNCTION IN DUCHENNE MUSCULAR DYSTROPHY [J].
Chew, K. ;
Farrar, M. ;
Widger, J. .
RESPIROLOGY, 2015, 20 :91-91
[43]   Steroid therapy and cardiac function in Duchenne muscular dystrophy [J].
Markham, LW ;
Spicer, RL ;
Khoury, PR ;
Wong, BL ;
Mathews, KD ;
Cripe, LH .
PEDIATRIC CARDIOLOGY, 2005, 26 (06) :768-771
[44]   Family function in families of children with Duchenne muscular dystrophy [J].
Chen, Jih-Yuan ;
Clark, Mary-Jo .
FAMILY & COMMUNITY HEALTH, 2007, 30 (04) :296-304
[45]   ASSESSMENT OF LOCOMOTOR FUNCTION IN YOUNG BOYS WITH DUCHENNE MUSCULAR-DYSTROPHY [J].
SMITH, RA ;
NEWCOMBE, RG ;
SIBERT, JR ;
HARPER, PS .
MUSCLE & NERVE, 1991, 14 (05) :462-469
[46]   The effect of posterior spinal fusion on respiratory function in Duchenne muscular dystrophy [J].
Alexander, W. M. ;
Smith, M. ;
Freeman, B. J. C. ;
Sutherland, L. M. ;
Kennedy, J. D. ;
Cundy, P. J. .
EUROPEAN SPINE JOURNAL, 2013, 22 (02) :411-416
[47]   EFFECTS OF UPPER EXTREMITY DYNAMIC EXERCISE ON RESPIRATORY FUNCTION AND QUALITY OF LIFE IN DUCHENNE MUSCULAR DYSTROPHY [J].
Alemdaroglu, Ipek ;
Karaduman, Ayse ;
Yilmaz, Oznur ;
Topaloglu, Haluk .
TURKISH JOURNAL OF PHYSIOTHERAPY REHABILITATION-FIZYOTERAPI REHABILITASYON, 2014, 25 (02) :78-85
[48]   Cognition trajectory in Duchenne muscular dystrophy [J].
Tony, Abeer A. ;
Abdelrashid, Sara ;
Ahmed, Hoda S. ;
Khodair, Mohamed Rizk .
EGYPTIAN JOURNAL OF NEUROLOGY PSYCHIATRY AND NEUROSURGERY, 2024, 60 (01)
[49]   EARLY LOWER-LIMB SURGERY IN DUCHENNE MUSCULAR-DYSTROPHY [J].
RICCIO, V ;
RICCARDI, G ;
DEMARTINO, MC ;
STANZIONE, P ;
MARRONE, G .
JOURNAL OF PEDIATRIC ORTHOPAEDICS-PART B, 1992, 1 (02) :131-134
[50]   Survival of patients with Duchenne muscular dystrophy [J].
San Martin P, Pamela ;
Solis F, Fresia ;
Cavada Ch, Gabriel .
REVISTA CHILENA DE PEDIATRIA-CHILE, 2018, 89 (04) :477-483