Juvenile granulosa cell tumor arising in ovarian adenosarcoma: an unusual form of sarcomatous overgrowth

被引：9

作者：

Carleton, Claire ^{[1
]}

Houghton, Oisin P. ^{[1
]}

McCluggage, W. Glenn ^{[1
]}

机构：

[1] Belfast Hlth & Social Care Trust, Dept Pathol, Belfast BT12 6BA, Antrim, North Ireland

来源：

HUMAN PATHOLOGY | 2015年 / 46卷 / 04期

关键词：

Ovary; Adenosarcoma; Juvenile granulosa cell tumor; Sex cord; Immunohistochemistry; CLINICOPATHOLOGICAL ANALYSIS; MULLERIAN ADENOSARCOMA; UTERUS; ELEMENTS; MUTATION; FOXL2;

D O I：

10.1016/j.humpath.2014.12.010

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

We report 2 ovarian neoplasms in women aged 58 and 69 years composed of an admixture of adenosarcoma and a predominant stromal component morphologically and immunohistochemically in keeping with juvenile granulosa cell tumor. As far as we are aware, this association has not been reported previously. We speculate that, in both cases, the juvenile granulosa cell tumor component arose from the adenosarcoma as an unusual form of sarcomatous overgrowth of sex cord elements. (C) 2015 Elsevier Inc. All rights reserved.

引用

页码：614 / 619

页数：6

共 16 条

[1] MULLERIAN ADENOSARCOMAS OF THE UTERUS WITH SEX CORD-LIKE ELEMENTS - A CLINICOPATHOLOGIC ANALYSIS OF 8 CASES [J].

CLEMENT, PB ;

SCULLY, RE .

AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 1989, 91 (06) :664-672

[2] MULLERIAN ADENOSARCOMAS OF THE UTERUS WITH SARCOMATOUS OVERGROWTH - A CLINICOPATHOLOGICAL ANALYSIS OF 10 CASES [J].

CLEMENT, PB .

AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1989, 13 (01) :28-38

[3]

CLEMENT PB, 1974, CANCER-AM CANCER SOC, V34, P1138, DOI 10.1002/1097-0142(197410)34:4<1138::AID-CNCR2820340425>3.0.CO

[4]

2-9

[5] MULLERIAN ADENOSARCOMA OF THE UTERUS - A CLINICOPATHOLOGICAL ANALYSIS OF 100 CASES WITH A REVIEW OF THE LITERATURE [J].

CLEMENT, PB ;

SCULLY, RE .

HUMAN PATHOLOGY, 1990, 21 (04) :363-381

[6]

CZERNOBILSKY B, 1982, DIAGN GYNECOL OBSTET, V4, P25

[7] Ovarian serous cystadenofibroma with stromal sex cord elements: Report of a unique case [J].

Dillon, Katrina ;

Boyde, Adam ;

Murphy, John K. ;

McCluggage, W. Glenn .

INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, 2006, 25 (04) :336-339

[8]

Eichhom HI, 2002, AM J SURG PATHOL, V26, P1243

[9] Mullerian Adenosarcoma of the Female Genital Tract [J].

McCluggage, W. Glenn .

ADVANCES IN ANATOMIC PATHOLOGY, 2010, 17 (02) :122-129

[10] Combined adult granulosa cell tumor and mucinous cystadenoma of the ovary: Granulosa cell tumor with heterologous mucinous elements [J].

McKenna, M ;

Kenny, B ;

Dorman, G ;

McCluggage, WG .

INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, 2005, 24 (03) :224-227

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