Dammarane triterpenoid glycosides in Bacopa monnieri: A review on chemical diversity and bioactivity

被引:27
作者
Bhandari, Pamita [1 ]
Sendri, Nitisha [1 ]
Devidas, Shinde Bhagatsing [1 ]
机构
[1] Inst Himalayan Bioresource Technol, CSIR, Nat Prod Chem & Proc Dev, Palampur, Himachal Prades, India
关键词
Bacopa monnieri; Plantaginaceae; Dammarane triterpenoids; Structure elucidation; Biological activity; IN-VITRO EVALUATION; BACOSIDE-A; OXIDATIVE STRESS; STANDARDIZED EXTRACT; CIGARETTE-SMOKE; QUANTITATIVE-DETERMINATION; PHENYLETHANOID GLYCOSIDES; ISOENZYME PATTERNS; MASS-SPECTROMETRY; CHRONIC EXPOSURE;
D O I
10.1016/j.phytochem.2020.112276
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Bacopa monnieri (L.) is a reputed medicinal herb in traditional system of medicine of India, where it is used as nervine tonic to sharpen intellect and memory. This review discusses chemical characterization of dammarane triterpenoid glycosides which are well accepted for improvement in memory and for potential pharmacological activities. In addition, this review provides information on the chemical composition of specialized metabolites of B. monnieri and in the formulations by different analytical techniques. This comprehensive review covers literature up to 2019 with an emphasis on structural characterization of dammarane triterpenoid glycosides by spectroscopic techniques, chemical composition by analytical methods and pharmacological activities.
引用
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页数:14
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