Complete Genome Sequence Analysis of a Natural Reassortant Infectious Bursal Disease Virus in China

被引：21

作者：

Chen, Feng ^{[1
]}

Liu, Jiajia ^{[1
]}

Yan, Zhuanqiang ^{[1
]}

Liu, Di ^{[1
]}

Ji, Jun ^{[1
]}

Qin, Jianping ^{[2
]}

Li, Haiyan ^{[2
]}

Ma, Jingyun ^{[1
]}

Bi, Yingzuo ^{[1
]}

Xie, Qingmei ^{[1
]}

机构：

[1] S China Agr Univ, Coll Anim Sci, Guangzhou, Guangdong, Peoples R China

[2] Guangdong Wens Foodstuffs Grp Co Ltd, Yunfu, Guangdong, Peoples R China

来源：

JOURNAL OF VIROLOGY | 2012年 / 86卷 / 21期

关键词：

ANTIGENICITY;

D O I：

10.1128/JVI.02043-12

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A novel isolate of infectious bursal disease virus (IBDV) was designated GX-NN-L. The GX-NN-L IBDV was a very virulent infectious bursal disease virus (vvIBDV) isolated from broiler flocks in Guangxi province, China, in 2011. The GX-NN-L IBDV caused high mortality, immunosuppression, low weight gain, and bursal atrophy in commercial broilers. Here, we report the complete genome sequence of the GX-NN-L IBDV, a reassortment strain with segments A and B derived from very virulent strains and attenuated IBDV, respectively. These findings from this study provide additional insights into the genetic exchange between attenuated and very virulent strains of IBDV and continuous monitoring of the spread of the virus in chicken.

引用

页码：11942 / 11943

页数：2