Silk materials at the convergence of science, sustainability, healthcare, and technology

被引:50
作者
Guidetti, Giulia [1 ]
d'Amone, Luciana [1 ]
Kim, Taehoon [1 ]
Matzeu, Giusy [1 ,2 ]
Mogas-Soldevila, Laia [4 ]
Napier, Bradley [1 ]
Ostrovsky-Snider, Nicholas [1 ]
Roshko, Jeffery [1 ]
Ruggeri, Elisabetta [1 ]
Omenetto, Fiorenzo G. [1 ,2 ,3 ,5 ,6 ]
机构
[1] Tufts Univ, Dept Biomed Engn, Silklab, Medford, MA 02155 USA
[2] Tufts Univ, Lab Living Devices, Medford, MA 02155 USA
[3] Tufts Univ, Ctr Appl Brain & Cognit Sci, Medford, MA 02155 USA
[4] Univ Penn, Stuart Weitzman Sch Design, Philadelphia, PA 19104 USA
[5] Tufts Univ, Dept Phys, Medford, MA 02155 USA
[6] Tufts Univ, Dept Elect & Comp Engn, Medford, MA 02155 USA
关键词
BOMBYX-MORI SILK; FIBROIN-COATED LIPOSOMES; SUSTAINED-RELEASE; MECHANICAL-PROPERTIES; DRUG-DELIVERY; CROSS-LINKING; STEM-CELLS; MOLECULAR-WEIGHT; FOOD WASTE; OPTICALLY TRANSPARENT;
D O I
10.1063/5.0060344
中图分类号
O59 [应用物理学];
学科分类号
摘要
Over the past few decades, Bombyx mori silk fibroin has become a ubiquitous material for applications ranging from biomedical devices to optics, electronics, and sensing, while also showing potential in the food supply chain and being re-engineered as a functional material for architecture and design-related applications. Its widespread use derives from its unique properties, including biocompatibility, edibility, optical transparency, stabilization of labile compounds, and the ability to controllably change conformation and degrade in a programmed way. This review discusses recent and pivotal silk-based devices in which the presence of silk brings added value in terms of functionality, as demonstrated in a broad variety of fields. First, it gives an overview of silk's natural structure and main properties in terms of cross-linking, biocompatibility, and biodegradability to provide the reader with the necessary toolbox to fully make use of silk's multifaceted properties. Then, multifunctional silk-based devices are discussed highlighting the advantage of using silk over more traditional materials. Representative devices from both established and emerging applications for silk are examined. Finally, a roadmap for the next generation of silk-based devices is laid out.
引用
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页数:50
相关论文
共 554 条
[1]   Gold nanorods reinforced silk fibroin nanocomposite for peripheral nerve tissue engineering applications [J].
Afjeh-Dana, Elham ;
Naserzadeh, Parvaneh ;
Nazari, Hojjatollah ;
Mottaghitalab, Fatemeh ;
Shabani, Ronak ;
Aminii, Naser ;
Mehravi, Bita ;
Rostami, Fatemeh Tajik ;
Joghataei, Mohammad Taghi ;
Mousavizadeh, Kazem ;
Ashtari, Khadijeh .
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2019, 129 :1034-1039
[2]  
Agarwal N, 1997, J APPL POLYM SCI, V63, P401
[3]   A 3D Printable Electroconductive Biocomposite Bioink Based on Silk Fibroin-Conjugated Graphene Oxide [J].
Ajiteru, Olatunji ;
Sultan, Tipu ;
Lee, Young Jin ;
Seo, Ye Been ;
Hong, Heesun ;
Lee, Ji Seung ;
Lee, Hanna ;
Suh, Ye Ji ;
Ju, Hyung Woo ;
Lee, Ok Joo ;
Park, Hae Sang ;
Jang, Moongyu ;
Kim, Soon Hee ;
Park, Chan Hum .
NANO LETTERS, 2020, 20 (09) :6873-6883
[4]   Macroporous Silk Fibroin Cryogels [J].
Ak, Fatih ;
Oztoprak, Zeynep ;
Karakutuk, Ilknur ;
Okay, Oguz .
BIOMACROMOLECULES, 2013, 14 (03) :719-727
[5]   Silk-based biomaterials [J].
Altman, GH ;
Diaz, F ;
Jakuba, C ;
Calabro, T ;
Horan, RL ;
Chen, JS ;
Lu, H ;
Richmond, J ;
Kaplan, DL .
BIOMATERIALS, 2003, 24 (03) :401-416
[6]   Rapid Nanoimprinting of Silk Fibroin Films for Biophotonic Applications [J].
Amsden, Jason J. ;
Domachuk, Peter ;
Gopinath, Ashwin ;
White, Robert D. ;
Dal Negro, Luca ;
Kaplan, David L. ;
Omenetto, Fiorenzo G. .
ADVANCED MATERIALS, 2010, 22 (15) :1746-+
[7]   Spectral analysis of induced color change on periodically nanopatterned silk films [J].
Amsden, Jason J. ;
Perry, Hannah ;
Boriskina, Svetlana V. ;
Gopinath, Ashwin ;
Kaplan, David L. ;
Dal Negro, Luca ;
Omenetto, Fiorenzo G. .
OPTICS EXPRESS, 2009, 17 (23) :21271-21279
[8]   Stretchable, Transparent Electrodes as Wearable Heaters Using Nanotrough Networks of Metallic Glasses with Superior Mechanical Properties and Thermal Stability [J].
An, Byeong Wan ;
Gwak, Eun-Ji ;
Kim, Kukjoo ;
Kim, Young-Cheon ;
Jang, Jiuk ;
Kim, Ju-Young ;
Park, Jang-Ung .
NANO LETTERS, 2016, 16 (01) :471-478
[9]  
An YH., 1999, MECH TESTING BONE BO
[10]  
[Anonymous], 2012, 2012 IEEE 3 LAT AM S