Comparison of the seroprevalence of human metapneumovirus and human respiratory syncytial virus

被引：50

作者：

Ebihara, T ^{[1
]}

Endo, R ^{[1
]}

Kikuta, H ^{[1
]}

Ishiguro, N ^{[1
]}

Ishiko, H ^{[1
]}

Kobayashi, K ^{[1
]}

机构：

[1] Hokkaido Univ, Sch Med, Dept Pediat, Kita Ku, Sapporo, Hokkaido 0608638, Japan

来源：

JOURNAL OF MEDICAL VIROLOGY | 2004年 / 72卷 / 02期

关键词：

human metapneumovirus; human respiratory syncytial virus; seroprevalence;

D O I：

10.1002/jmv.10572

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Human metapneumovirus (hMPV) is a virus that induces human respiratory syncytial virus (hRSV)-like illnesses, ranging from upper respiratory tract infection to severe bronchiolitis and pneumonia. The 100 serum samples from children aged 1 month to 5 years were tested for the presence of hMPV and hRSV antibodies using an indirect immunofluorescence assay and a neutralizing-antibody assay, respectively. The seroprevalence of hMPV was significantly lower than that of hRSV in children over 4-months-old (43% vs. 60%, P < 0.025), and the difference was particularly notable between the ages of 4 months and 1 year (11% vs. 48%, P = 0.006). The results suggest that primary infection with hMPV occurs somewhat later than that with hRSV. (C) 2004 Wiley-Liss, Inc.

引用

页码：304 / 306

页数：3

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