Luminescent Ruthenium(II) Polypyridyl Functionalized Gold Nanoparticles; Their DNA Binding Abilities and Application As Cellular Imaging Agents

被引：140

作者：

Elmes, Robert B. P. ^{[2
,3
]}

Orange, Kim N. ^{[1
,3
]}

Cloonan, Suzanne M. ^{[1
,3
]}

Williams, D. Clive ^{[1
,3
]}

Gunnlaugsson, Thorfinnur ^{[2
,3
]}

机构：

[1] Trinity Coll Dublin, Sch Biochem & Immunol, Dublin 2, Ireland

[2] Trinity Coll Dublin, Sch Chem, Ctr Synth & Chem Biol, Dublin 2, Ireland

[3] Trinity Coll Dublin, Inst Biomed Sci, Dublin 2, Ireland

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2011年 / 133卷 / 40期

基金：

爱尔兰科学基金会;

关键词：

TRANSITION-METAL-COMPLEXES; RECOGNITION; INTERCALATORS; FLUORESCENCE;

D O I：

10.1021/ja2061159

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis and photophysical and biological investigation of Ru(II)-polypyridyl stabilized water-soluble, luminescent gold nanoparticles (AuNPs) are described. These structures bind to DNA and undergo rapid cellular uptake, being localized within the cell cytoplasm and nucleus within 4 h.

引用

页码：15862 / 15865

页数：4

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