C5-selective trifluoromethylation of 8-amino quinolines via photoredox catalysis

被引：36

作者：

Tian, Chao ^{[1
]}

Yang, Li-Ming ^{[1
]}

Tian, Hai-Tao ^{[1
]}

An, Guang-Hui ^{[1
,2
]}

Li, Guang-Ming ^{[1
]}

机构：

[1] Heilongjiang Univ, Sch Chem & Mat Sci, Key Lab Funct Inorgan Mat Chem MOE, 74 Xuefu Rd, Harbin 150080, Heilongjiang, Peoples R China

[2] Harbin Engn Univ, Coll Mat Sci & Chem Engn, Harbin 150001, Heilongjiang, Peoples R China

来源：

JOURNAL OF FLUORINE CHEMISTRY | 2019年 / 219卷

基金：

中国国家自然科学基金;

关键词：

Trifluoromethylation; 8-Aminoquinolines; Photoredox catalysis; Para-selective C-H activation; C-H TRIFLUOROMETHYLATION; PERFLUOROALKYLATION; AMINOQUINOLINES; FLUORINATION; REAGENT;

D O I：

10.1016/j.jfluchem.2018.12.011

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A new protocol for C5-selective C-H trifluoromethylation of 8-aminoquinolines via photoredox catalysis was developed. It allows rapid access to various C5-trifluoromethyl 8-amino quinoline derivatives in MeCN/H2O enabled by Eosin Y as photocatalysts.

引用

页码：23 / 28

页数：6

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