Intravascular Optical Imaging Technology for Investigating the Coronary Artery

被引：104

作者：

Suter, Melissa J. ^{[1
,2
]}

Nadkarni, Seemantini K. ^{[1
,3
]}

Weisz, Giora ^{[4
,5
]}

Tanaka, Atsushi ^{[1
,3
]}

Jaffer, Farouc A. ^{[1
,6
,7
]}

Bouma, Brett E. ^{[1
,3
,8
]}

Tearney, Guillermo J. ^{[1
,8
,9
]}

机构：

[1] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Wellman Ctr Photomed, Boston, MA 02114 USA

[2] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Pulm & Crit Care Unit, Boston, MA 02114 USA

[3] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Dermatol, Boston, MA 02114 USA

[4] Columbia Univ, Ctr Intervent Vasc Therapy, New York Presbyterian Hosp, New York, NY USA

[5] Cardiovasc Res Fdn, New York, NY USA

[6] Cardiovasc Res Ctr, Div Cardiol, Boston, MA USA

[7] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Ctr Mol Imaging Res, Boston, MA 02114 USA

[8] Harvard Univ, MIT, Div Hlth Sci & Technol, Cambridge, MA 02139 USA

[9] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Pathol, Boston, MA 02114 USA

来源：

JACC-CARDIOVASCULAR IMAGING | 2011年 / 4卷 / 09期

关键词：

intracoronary; optical diagnostics; optical imaging; NEAR-INFRARED SPECTROSCOPY; LASER-INDUCED FLUORESCENCE; SIROLIMUS-ELUTING STENT; FIBROUS CAP THICKNESS; IN-VIVO DETECTION; COHERENCE TOMOGRAPHY; ATHEROSCLEROTIC PLAQUES; VULNERABLE PLAQUE; REAL-TIME; NEOINTIMAL COVERAGE;

D O I：

10.1016/j.jcmg.2011.03.020

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

There is an ever-increasing demand for new imaging methods that can provide additional information about the coronary wall to better characterize and stratify high-risk plaques, and to guide interventional and pharmacologic management of patients with coronary artery disease. While there are a number of imaging modalities that facilitate the assessment of coronary artery pathology, this review paper focuses on intravascular optical imaging modalities that provide information on the microstructural, compositional, biochemical, biomechanical, and molecular features of coronary lesions and stents. The optical imaging modalities discussed include angioscopy, optical coherence tomography, polarization sensitive-optical coherence tomography, laser speckle imaging, near-infrared spectroscopy, time-resolved laser induced fluorescence spectroscopy, Raman spectroscopy, and near-infrared fluorescence molecular imaging. Given the wealth of information that these techniques can provide, optical imaging modalities are poised to play an increasingly significant role in the evaluation of the coronary artery in the future. (J Am Coll Cardiol Img 2011;4:1022-39) (C) 2011 by the American College of Cardiology Foundation

引用

页码：1022 / 1039

页数：18

共 155 条

[81] Detection of lipid pool, thin fibrous cap, and inflammatory cells in human aortic atherosclerotic plaques by near-infrared spectroscopy [J].