β-TCP Versus Autologous Bone for Repair of Alveolar Clefts in a Goat Model

被引：31

作者：

de Ruiter, Ad ^{[1
]}

Meijer, Gert ^{[2
,3
]}

Dormaar, Titiaan ^{[1
]}

Janssen, Nard ^{[1
]}

van der Bilt, Andries ^{[1
]}

Slootweg, Piet ^{[4
]}

de Bruijn, Joost ^{[5
]}

van Rijn, Linda ^{[6
]}

Koole, Ronald ^{[1
]}

机构：

[1] Univ Med Ctr Utrecht, Dept Oral & Maxillofacial Surg, Utrecht, Netherlands

[2] Radboud Univ Nijmegen, Med Ctr, Dept Oral & Maxillofacial Surg, Nijmegen, Netherlands

[3] Radboud Univ Nijmegen, Med Ctr, Dept Implantol & Periodontol, Nijmegen, Netherlands

[4] Radboud Univ Nijmegen, Med Ctr, Dept Pathol, Nijmegen, Netherlands

[5] Queen Mary Univ London, Sch Engn & Mat Sci, London, England

[6] Xpand Biotechnol BV, Bilthoven, Netherlands

来源：

CLEFT PALATE-CRANIOFACIAL JOURNAL | 2011年 / 48卷 / 06期

关键词：

alveolar cleft; beta-TCP; bone grafting; bone substitute; ORTHODONTIC TOOTH MOVEMENT; APICAL ROOT RESORPTION; PLATELET-RICH PLASMA; AUTOGENOUS BONE; TRICALCIUM PHOSPHATE; MAXILLARY SINUS; DEFECTS; GRAFTS; AUGMENTATION; RECONSTRUCTION;

D O I：

10.1597/09-219

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Objective: The aim of this study in goats was to test the hypothesis that a novel synthetic bone substitute beta tricalcium phosphate (beta-TCP) can work as well as autologous bone harvested from the iliac crest for grafting and repair of alveolar clefts. Design: Ten adult Dutch milk goats (Capra hircus) were used in a split-mouth study design. Main outcome measures: Volumetric histologic assessment of new bone formation and radiographic measurement of orthodontic movement of teeth in a formerly created alveolar cleft. Conclusions: The synthetic bone substitute b-TCP was shown to result in bone healing similar to that of iliac crest bone. The surgical, orthodontic, and histologic results now warrant the testing of b-TCP in the human cleft situation.

引用

页码：654 / 662

页数：9

共 45 条

[1] Identification of orthodontic patients at risk of severe apical root resorption [J].

Artun, Jon ;

Van 't Hullenaar, Ron ;

Doppel, Diane ;

Kuijpers-Jagtman, Anne M. .

AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS, 2009, 135 (04) :448-455

[2] Management of alveolar clefts [J].

Bajaj, AK ;

Wongworawat, AA ;

Punjabi, A .

JOURNAL OF CRANIOFACIAL SURGERY, 2003, 14 (06) :840-846

[3]

Binger T, 2003, CLEFT PALATE-CRAN J, V40, P561, DOI 10.1597/1545-1569(2003)040<0561:SDTRAW>2.0.CO

[4]

[5] Morbidity of chin bone transplants used for reconstructing alveolar defects in cleft patients [J].

Booij, A ;

Raghoebar, GM ;

Jansma, J ;

Kalk, WWI ;

Vissink, A .

CLEFT PALATE-CRANIOFACIAL JOURNAL, 2005, 42 (05) :533-538

[6] A literature review on biomaterials in sinus augmentation procedures [J].

Browaeys, Hilde ;

Bouvry, Peter ;

De Bruyn, Hugo .

CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH, 2007, 9 (03) :166-177

[7] Reconstruction of mandibular defects using autografts combined with demineralized bone matrix and cancellous allograft [J].

Canter, Halil Ibrahim ;

Vargel, Ibrahim ;

Mavili, M. Emin .

JOURNAL OF CRANIOFACIAL SURGERY, 2007, 18 (01) :95-100

[8] In vitro evaluation of freeze-dried bone allografts combined with platelet rich plasma and human bone marrow stromal cells for tissue engineering [J].

Cenni, Elisabetta ;

Perut, Francesca ;

Ciapetti, Gabriela ;

Savarino, Lucia ;

Dallari, Dante ;

Cenacchi, Annarita ;

Stagni, Cesare ;

Giunti, Armando ;

Fornasari, Pier Maria ;

Baldini, Nicola .

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2009, 20 (01) :45-50

[9] Tissue engineering for bone defect heating: An update on a multi-component approach [J].

Drosse, Inga ;

Volkmer, Elias ;

Capanna, Rodolfo ;

De Biase, Pietro ;

Mutschler, Wolf ;

Schieker, Matthias .

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 2008, 39 :S9-S20

[10] Detection of apical root resorption after orthodontic treatment by using panoramic radiography and cone-beam computed tomography of super-high resolution [J].

Dudic, Alexander ;

Giannopoulou, Catherine ;

Leuzinger, Michael ;

Kiliaridis, Stavros .

AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS, 2009, 135 (04) :434-437

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