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Species-Specific Interactions of Src Family Tyrosine Kinases Regulate Chlamydia Intracellular Growth and Trafficking
被引:4
作者:
Elwell, Cherilyn A.
[1
,2
]
Kierbel, Arlinet
[3
]
Engel, Joanne N.
[1
,2
,4
]
机构:
[1] Univ Calif San Francisco, Dept Med, San Francisco, CA 94143 USA
[2] Univ Calif San Francisco, Dept Microbiol & Immunol, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Microbial Pathogenesis & Host Def Program, San Francisco, CA 94143 USA
[4] Inst Pasteur, Montevideo, Uruguay
来源:
关键词:
HELICOBACTER-PYLORI CAGA;
ESCHERICHIA-COLI RECEPTOR;
MICROTUBULE NETWORK;
TRACHOMATIS TARP;
C-FYN;
PHOSPHORYLATION;
PROTEIN;
CELLS;
ABNORMALITIES;
INFECTION;
D O I:
10.1128/mBio.00082-11
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
Src family kinases (SFKs) regulate key cellular processes and are emerging as important targets for intracellular pathogens. In this commentary, we briefly review the role of SFKs in bacterial pathogenesis and highlight new work on the role of SFKs during the intracellular cycle of Chlamydia species.
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页数:2
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