Recent Development of Extremophilic Bacteria and Their Application in Biorefinery

被引：88

作者：

Zhu, Daochen ^{[1
,2
]}

Adebisi, Wasiu Adewale ^{[1
]}

Ahmad, Fiaz ^{[1
]}

Sethupathy, Sivasamy ^{[1
]}

Danso, Blessing ^{[1
]}

Sun, Jianzhong ^{[1
]}

机构：

[1] Jiangsu Univ, Biofuels Inst, Sch Environm & Safety Engn, Zhenjiang, Jiangsu, Peoples R China

[2] Guangdong Inst Microbiol, State Key Lab Appl Microbiol Southern China, Guangdong Prov Key Lab Microbial Culture Collect, Guangdong Open Lab Appl Microbiol, Guangzhou, Peoples R China

来源：

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY | 2020年 / 8卷

基金：

中国国家自然科学基金; 国家重点研发计划;

关键词：

biofuel; biorefinery; extremophiles; extremozymes; synthetic biology; ADAPTED BETA-GALACTOSIDASE; OF-THE-ART; LIGNOCELLULOSIC BIOMASS; BIOTECHNOLOGICAL APPLICATIONS; THERMOSTABLE ENDOGLUCANASE; THERMOPHILIC BACTERIA; LIGNIN VALORIZATION; OXIDIZING BACTERIA; ETHANOL-PRODUCTION; LIPID PRODUCTION;

D O I：

10.3389/fbioe.2020.00483

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The biorefining technology for biofuels and chemicals from lignocellulosic biomass has made great progress in the world. However, mobilization of laboratory research toward industrial setup needs to meet a series of criteria, including the selection of appropriate pretreatment technology, breakthrough in enzyme screening, pathway optimization, and production technology, etc. Extremophiles play an important role in biorefinery by providing novel metabolic pathways and catalytically stable/robust enzymes that are able to act as biocatalysts under harsh industrial conditions on their own. This review summarizes the potential application of thermophilic, psychrophilic alkaliphilic, acidophilic, and halophilic bacteria and extremozymes in the pretreatment, saccharification, fermentation, and lignin valorization process. Besides, the latest studies on the engineering bacteria of extremophiles using metabolic engineering and synthetic biology technologies for high-efficiency biofuel production are also introduced. Furthermore, this review explores the comprehensive application potential of extremophiles and extremozymes in biorefinery, which is partly due to their specificity and efficiency, and points out the necessity of accelerating the commercialization of extremozymes.

引用

页数：18