[1] Natl Yang Ming Univ, Sch Med, Inst Pharmacol, Taipei 11221, Taiwan
[2] Natl Def Med Ctr, Grad Inst Life Sci, Taipei 11490, Taiwan
[3] Natl Yang Ming Univ, Sch Biomed Sci & Engn, Dept Biomed Image & Radiol Sci, Taipei 11221, Taiwan
[4] Acad Sinica, Inst Biomed Sci, Taipei 11529, Taiwan
[5] Taipei Vet Gen Hosp, Dept Med Res & Educ, Taipei 11217, Taiwan