Inflammation, immunity, and vaccines for Helicobacter infection

被引:20
|
作者
Permin, H [1 ]
Andersen, LP
机构
[1] Bispebjerg Hosp, Dept Internal Med, DK-2400 Copenhagen, Denmark
[2] Copenhagen Univ Hosp, Rigshosp, Dept Clin Microbiol 9301, Copenhagen, Denmark
关键词
inflammation; immunity; vaccine; Helicobacter;
D O I
10.1111/j.1523-5378.2005.00337.x
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Pro-inflammatory cytokines such as IL-18, IFN-gamma, and IL-1 beta play a significant role in the inflammation induced by Helicobacter. During the recent years of H. pylori research, the main focus has been on development of vaccines for therapeutic or prophylactic use against the infection. Both bacterial components of H. pylori as well as engineered vaccines have been tested as well as different forms of administration including systemic and oral/intranasal pathways.
引用
收藏
页码:21 / 25
页数:5
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