How common is true resistant hypertension?

被引:35
作者
Bunker, J. [1 ]
Callister, W. [1 ]
Chang, C-L [2 ]
Sever, P. S. [2 ]
机构
[1] Imperial Coll Healthcare NHS Trust, London, England
[2] Univ London Imperial Coll Sci Technol & Med, London, England
关键词
D O I
10.1038/jhh.2010.108
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
Resistant hypertension, defined as failure to achieve goal blood pressures in patients taking optimal or maximum tolerated doses of three or more antihypertensive drugs, is estimated to occur in about 25% of hypertensive patients on treatment. Poor adherence with treatment is considered to have an important role leading to apparent drug resistant hypertension. We have demonstrated that observed drug taking ('tablet feed'), followed by close monitoring of blood pressure in a clinic environment, together with ambulatory blood pressure monitoring, identifies a high proportion of patients (about two-thirds) of those presenting with resistant hypertension, whose persistently elevated blood pressure levels are due to poor adherence with drug treatment.
引用
收藏
页码:137 / 140
页数:4
相关论文
共 5 条
[1]   Continued Improvement in Hypertension Management in England Results From the Health Survey for England 2006 [J].
Falaschetti, Emanuela ;
Chaudhury, Moushumi ;
Mindell, Jennifer ;
Poulter, Neil .
HYPERTENSION, 2009, 53 (03) :480-486
[2]  
Nunes V., 2009, Clinical Guidelines and Evidence Review for Medicines Adherence: involving patients in decisions about prescribed medicines and supporting adherence
[3]  
WILLIAMS B, BHS GUIDELINES UNPUB
[4]   Hypertension treatment and control in five European Countries, Canada, and the United States [J].
Wolf-Maier, K ;
Cooper, RS ;
Kramer, H ;
Banegas, JR ;
Giampaoli, S ;
Joffres, MR ;
Poulter, N ;
Primatesta, P ;
Stegmayr, B ;
Thamm, M .
HYPERTENSION, 2004, 43 (01) :10-17
[5]   The global burden of chronic diseases - Overcoming impediments to prevention and control [J].
Yach, D ;
Hawkes, C ;
Gould, CL ;
Hofman, KJ .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 291 (21) :2616-2622