POINT SHEAR WAVE ELASTOGRAPHY FOR GRADING LIVER FIBROSIS: CAN THE NUMBER OF MEASUREMENTS BE REDUCED?

被引:2
作者
Durot, Isabelle [1 ]
Akhbardeh, Alireza [1 ]
Rosenberg, Jarrett [1 ]
Willmann, Juergen K. [1 ]
机构
[1] Stanford Univ, Sch Med, Dept Radiol, Stanford, CA 94305 USA
关键词
Ultrasound; Elastography; Liver stiffness; Liver fibrosis; Chronic liver disease; Screening; RADIATION FORCE IMPULSE; ULTRASOUND ELASTOGRAPHY; CLINICAL-USE; TRANSIENT ELASTOGRAPHY; ARFI ELASTOGRAPHY; WFUMB GUIDELINES; GLOBAL BURDEN; RECOMMENDATIONS; DISEASE;
D O I
10.1016/j.ultrasmedbio.2018.07.028
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
The aim of this study was to assess whether the number of liver point shear wave elastography (pSWE) measurements could be reduced compared with the currently recommended 10 valid measurements. Three thousand four hundred one pSWE examinations in patients with liver disease were performed with 10 consecutive valid measurements in liver segment 8. Liver fibrosis grading using published cutoff values were compared retrospectively using the median of 10 versus the first 1-9 measurements with Kendall's tau coefficient. Overall and binary (clinically significant [>= F2] versus non-significant [F0/F1]) fibrosis grading highly correlated when using 5-9 versus 10 valid measurements (tau = 0.96/0.95, p < 0.001). With the use of 5 valid measurements, a change in binary grading was observed in 87 of 3401 (2.6%) exams and only when velocities measured between 1.1 and 1.5 m/s. Therefore, using 5-9 valid measurements in pSWE of the liver results in a small portion of liver fibrosis grading misclassifications compared with use of 10 measurements and could help decrease scanning time, cost and discomfort in sonographers and patients. (E-mail: durot@atanford.edu) (C) 2018 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
引用
收藏
页码:2569 / 2577
页数:9
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