Association between PTPN22 and endometriosis

被引:24
作者
Ammendola, Maria [2 ]
Bottini, Nunzio [3 ,4 ]
Pietropolli, Adalgisa [2 ]
Saccucci, Patrizia [1 ]
Gloria-Bottini, Fulvia [1 ]
机构
[1] Hosp Univ Rome Tor Vergata, Dept Biopathol & Imaging Diagnost, Div Human Populat Biopathol & Environm Pathol, Sch Med, Rome, Italy
[2] Hosp Univ Rome Tor Vergata, Div Obstet & Gynecol, Dept Surg, Sch Med, Rome, Italy
[3] Univ So Calif, Dept Orthoped Surg, Los Angeles, CA USA
[4] Univ So Calif, Inst Med Genet, Los Angeles, CA USA
关键词
D O I
10.1016/j.fertnstert.2007.04.008
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
PTPN22 is currently one of the few known shared-autoimmunity genes and is therefore a candidate marker for endometriosis. Our data show that female carriers of the PTPN22*T variant are significantly more susceptible to endometriosis than controls. (Fertil Steril (c) 2008;89:993-4. (c) 2008 by American Society for Reproductive Medicine.)
引用
收藏
页码:993 / 994
页数:2
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