Synthesis and coating methods of biocompatible iron oxide/gold nanoparticle and nanocomposite for biomedical applications

被引：55
作者：
Dheyab, Mohammed Ali [1 ,2 ]
Aziz, Azlan Abdul [1 ,2 ]
Jameel, Mahmood S. [1 ,2 ]
Abu Noqta, Osama [1 ,2 ]
Mehrdel, Baharak [1 ,2 ]
机构：
[1] Univ Sains Malaysia, Inst Res MolecularMed INFORMM, Nanobiotechnol Res & Innovat NanoBRI, George Town 11800, Malaysia
[2] Univ Sains Malaysia, Sch Phys, Nanooptoelect Res & Technol Lab NORLab, George Town 11800, Malaysia
来源：
CHINESE JOURNAL OF PHYSICS | 2020年 / 64卷
关键词：
Iron oxide (Fe3O4); Core/shell nanocomposite; Surface modification; Au coated Fe3O4; Biomedical applications; COATED MAGNETIC NANOPARTICLES; SIZE-CONTROLLED SYNTHESIS; MODIFIED SUPERPARAMAGNETIC NANOPARTICLES; ASSISTED THERMAL-DECOMPOSITION; CORE-SHELL NANOPARTICLES; T-2 CONTRAST AGENT; ONE-POT SYNTHESIS; FE3O4; NANOPARTICLES; DRUG-DELIVERY; SONOCHEMICAL SYNTHESIS;
D O I：
10.1016/j.cjph.2019.11.014
中图分类号：
O4 [物理学];
学科分类号：
0702 ;
摘要：
This detailed review presents an overview of current research on the synthesis, surface modification, and applications of Iron oxide (Fe3O4) nanoparticles and iron oxide/gold (Fe3O4/Au) nanocomposites. The different synthesis techniques of Fe3O4 with various basic organic and inorganic modifications are presented. The applicability and role of inorganic and organic coating on iron oxide/gold core/shell schemes were explored. The trade-off between choices for surface functionalization related to specific applications such as imaging contrast agent, drug delivery carrier and therapeutic device using iron oxide/gold core/shell was also elaborated. The versatility of combining iron oxide/ and gold as nanocomposite as the choice for biomedical application is demonstrated in MRI, CT scan, drug delivery, biosensors, and hyperthermia application.
引用
收藏
页码：305 / 325
页数：21
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