Glutathione Facilitates Antibiotic Resistance and Photosystem I Stability during Exposure to Gentamicin in Cyanobacteria

被引：35
作者：
Cameron, Jeffrey C. [1 ]
Pakrasi, Himadri B. [1 ]
机构：
[1] Washington Univ, Dept Biol, St Louis, MO 63130 USA
来源：
APPLIED AND ENVIRONMENTAL MICROBIOLOGY | 2011年 / 77卷 / 10期
基金：
美国国家科学基金会;
关键词：
BLUE-GREEN-ALGAE; FREE-RADICALS; MECHANISM; GROWTH; IRON;
D O I：
10.1128/AEM.02542-10
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Understanding mechanisms of antibiotic resistance is important to the fields of biology and medicine. We find that glutathione contributes to antibiotic resistance in the cyanobacterium Synechocystis sp. PCC 6803. Our results also suggest that glutathione protects photosystem I from oxidative damage resulting from growth in the presence of gentamicin.
引用
收藏
页码：3547 / 3550
页数：4
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