Avian Leucosis Virus-Host Interaction: The Involvement of Host Factors in Viral Replication

被引:12
作者
Tang, Shuang [1 ,3 ]
Li, Jie [2 ]
Chang, Yung-Fu [2 ]
Lin, Wencheng [1 ,3 ]
机构
[1] South China Agr Univ, Coll Anim Sci, Guangdong Prov Key Lab Agroanim Genom & Mol Breedi, Guangzhou, Peoples R China
[2] Cornell Univ, Coll Vet Med, Dept Populat Med & Diagnost Sci, Ithaca, NY USA
[3] South China Agr Univ, Coll Anim Sci, Key Lab Chicken Genet Breeding & Reprod Minist Agr, Guangzhou, Peoples R China
来源
FRONTIERS IN IMMUNOLOGY | 2022年 / 13卷
基金
中国国家自然科学基金;
关键词
avian leukemia virus; interaction; immunosuppression; host factors; replication; PREMATURE STOP CODON; SUBGROUP-J; DECREASED SUSCEPTIBILITY; TVB RECEPTOR; INFECTION; SARCOMA; RESISTANCE; CHICKENS; DIFFERENTIATION; IDENTIFICATION;
D O I
10.3389/fimmu.2022.907287
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Avian leukosis virus (ALV) causes various diseases associated with tumor formation and decreased fertility. Moreover, ALV induces severe immunosuppression, increasing susceptibility to other microbial infections and the risk of failure in subsequent vaccination against other diseases. There is growing evidence showing the interaction between ALV and the host. In this review, we will survey the present knowledge of the involvement of host factors in the important molecular events during ALV infection and discuss the futuristic perspectives from this angle.
引用
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页数:7
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