The use of bone graft substitutes in large cancellous voids: Any specific needs?

被引：105

作者：

Faour, Omar ^{[2
]}

Dimitriou, Rozalia ^{[1
]}

Cousins, Charlotte A. ^{[1
]}

Giannoudis, Peter V. ^{[1
]}

机构：

[1] Univ Leeds, Leeds Gen Infirm, Acad Dept Trauma & Orthopaed Surg, Sch Med, Leeds LS1 3EX, W Yorkshire, England

[2] Clin Univ Hosp Valladolid, Dept Trauma & Orthopaed Surg, Valladolid, Spain

来源：

INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED | 2011年 / 42卷

关键词：

Cancellous voids; Bone defects; Allograft; Bone graft substitute; TIBIAL PLATEAU FRACTURES; CALCIUM-PHOSPHATE CEMENT; TRAUMA SURGERY; AUGMENTATION; LESIONS; FIXATION; FUSION;

D O I：

10.1016/j.injury.2011.06.020

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Bone graft is the second most common transplantation tissue, with blood being by far the commonest. Autograft is considered ideal for grafting procedures, providing osteoinductive growth factors, osteogenic cells and an osteoconductive scaffold. Limitations, however, exist regarding donor site morbidity and graft availability. Allograft on the other hand poses the risk of disease transmission. Synthetic graft substitutes lack osteoinductive or osteogenic properties. Composite grafts combine scaffolding properties with biological elements to stimulate cell proliferation and differentiation and eventually osteogenesis. We present here an overview of bone graft substitutes available for clinical application in large cancellous voids. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：S87 / S90

页数：4

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