Pneumococcal Meningitis Before and After Universal Vaccination With Pneumococcal Conjugate Vaccines 7/13, Impact on Pediatric Hospitalization in Public and Nonpublic Institutions, in Uruguay

被引：8

作者：

Catalina Pirez, Maria ^{[1
]}

Ines Mota, Maria ^{[2
]}

Giachetto, Gustavo ^{[1
]}

Sanchez Varela, Mercedes ^{[3
]}

Galazka, Jeannette ^{[4
]}

Gutierrez, Stella ^{[5
]}

Varela, Adriana ^{[2
]}

Picon, Teresa ^{[4
]}

Algorta, Gabriela ^{[2
]}

机构：

[1] Univ Republica, Fac Med, Hosp Pediat, Ctr Hosp Pereira Rossell, Montevideo, Uruguay

[2] Univ Republica, Fac Med, Ctr Hosp Pereira Rossell, Lab Microbiol, Montevideo, Uruguay

[3] British Hosp, Dept Pediat, Montevideo, Uruguay

[4] Asociac Espanola Primera Salud, Dept Atenc Integral Nino Nina & Adolescente, Montevideo, Uruguay

[5] Ctr Asistencial Sindicato Med Uruguay, Montevideo, Uruguay

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2017年 / 36卷 / 10期

关键词：

Streptococcus pneumoniae; meningitis; pneumococcal conjugate vaccine; CHILDREN; ENGLAND; DISEASE;

D O I：

10.1097/INF.0000000000001671

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

This is the first study showing the impact of 13-valent pneumococcal conjugate vaccine on pneumococcal meningitis in Latin America; a significant (63.5%) reduction in hospitalization was observed during the first 6 years after starting vaccination. A 90% reduction of pneumococcal conjugate vaccines 7/13 serotypes was observed (P < 0.0001). After vaccination, all strains were penicillin susceptible. Mortality had a reduction of 71%.

引用

页码：1000 / 1001

页数：2

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