The clinical utility of Xpert® MTB/RIF testing in induced sputum

被引：6

作者：

Chew, M. Y. ^{[1
,2
]}

Ng, J. ^{[1
,2
]}

Cai, H-M ^{[1
,2
]}

Lim, T. G. ^{[3
]}

Lim, T. K. ^{[1
,2
]}

机构：

[1] Natl Univ Singapore Hosp, Univ Med Cluster, Div Resp & Crit Care Med, Singapore, Singapore

[2] Natl Univ Singapore, Yong Loo Lin Sch Med, Dept Med, Singapore, Singapore

[3] Natl Univ Singapore Hosp, Dept Rehabil, Singapore, Singapore

来源：

INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | 2016年 / 20卷 / 12期

关键词：

Xpert((R)) MTB/RIF; induced sputum; diagnosis; treatment; pulmonary tuberculosis; TUBERCULOSIS; ACCURACY; FEASIBILITY; DIAGNOSIS; MULTICENTER;

D O I：

10.5588/ijtld.16.0123

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

We performed a prospective clinical audit in hospitalised patients with suspected pulmonary tuberculosis (PTB) with the objective of evaluating the accuracy and clinical utility of Xpert MTB/RIF in induced sputum in an intermediate-burden setting. Of 450 patients audited, 61 (13.6%) were diagnosed with PTB based on positive culture. The sensitivity, specificity and positive and negative predictive values for Xpert in smear-negative cases for induced sputum were respectively 75%, 99.5%, 94.7% and 97.0%. Xpert in induced sputum may facilitate diagnostic yield and expedite treatment in up to a quarter of PTB patients.

引用

页码：1668 / 1670

页数：3

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