Beating Bipolar: exploratory trial of a novel internet-based psychoeducational treatment for bipolar disorder

被引:78
作者
Smith, Daniel J. [1 ]
Griffiths, Emily [1 ]
Poole, Ria [1 ]
di Florio, Arianna [1 ]
Barnes, Emma [1 ]
Kelly, Mark J. [2 ]
Craddock, Nick [1 ]
Hood, Kerenza [2 ]
Simpson, Sharon [2 ]
机构
[1] Cardiff Univ, Sch Med, Dept Psychol Med & Neurol, Cardiff CF14 4DW, S Glam, Wales
[2] Cardiff Univ, Sch Med, Dept Primary Care & Publ Hlth, SE Wales Trials Unit, Cardiff CF14 4DW, S Glam, Wales
关键词
bipolar disorder; clinical trial; internet; patient education; quality of life; RATING-SCALE; RELIABILITY; DEPRESSION; INTERVIEW; EFFICACY; VALIDITY;
D O I
10.1111/j.1399-5618.2011.00949.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objectives: Psychoeducational approaches are promising interventions for the long-term management of bipolar disorder. In consultation with professionals, patients, and their families we have developed a novel web-based psychoeducational intervention for bipolar disorder called Beating Bipolar. We undertook a preliminary exploratory randomized trial to examine efficacy, feasibility and acceptability. Methods: This was an exploratory randomized controlled trial of Beating Bipolar (current controlled trials registration number: ISRCTN81375447). The control arm was treatment-as-usual and the a priori primary outcome measure was quality of life [measured by the brief World Health Organization Quality of Life (WHOQOL-BREF) scale]. Secondary outcomes included psychosocial functioning, insight, depressive and manic symptoms and relapse, and use of healthcare resources. Fifty participants were randomized to either the Beating Bipolar intervention plus treatment-as-usual or just treatment-as-usual. The intervention was delivered over a four-month period and outcomes were assessed six months later. Results: There was no significant difference between the intervention and control groups on the primary outcome measure (total WHOQOL-BREF score) but there was a modest improvement within the psychological subsection of the WHOQOL-BREF for the intervention group relative to the control group. There were no significant differences between the groups on any of the secondary outcome measures. Conclusions: Beating Bipolar is potentially a safe and engaging intervention which can be delivered remotely to large numbers of patients with bipolar disorder at relatively low cost. It may have a modest effect on psychological quality of life. Further work is required to establish the impact of this intervention on insight, knowledge, treatment adherence, self-efficacy and self-management skills.
引用
收藏
页码:571 / 577
页数:7
相关论文
共 24 条
[1]  
[Anonymous], 1998, PSYCHOL MED, V28, P551, DOI [DOI 10.1017/S0033291798006667, 10.1017/S0033291798006667]
[2]   Developing an online psychoeducation package for bipolar disorder [J].
Barnes, Emma ;
Simpson, Sharon ;
Griffiths, Emily ;
Hood, Kerry ;
Craddock, Nick ;
Smith, Daniel J. .
JOURNAL OF MENTAL HEALTH, 2011, 20 (01) :21-31
[3]  
Bauer M.S., 2003, LIFE GOALS PROGRAM S
[4]   Balance algorithm for cluster randomized trials [J].
Carter, Ben R. ;
Hood, Kerenza .
BMC MEDICAL RESEARCH METHODOLOGY, 2008, 8 (1)
[5]  
Cohen J., 1988, Statistical power analysis for the behavioral sciences, VSecond
[6]   Psychoeducation: improving outcomes in bipolar disorder [J].
Colom, F ;
Lam, D .
EUROPEAN PSYCHIATRY, 2005, 20 (5-6) :359-364
[7]   Group psychoeducation for stabilised bipolar disorders: 5-year outcome of a randomised clinical trial [J].
Colom, F. ;
Vieta, E. ;
Sanchez-Moreno, J. ;
Palomino-Otiniano, R. ;
Reinares, M. ;
Goikolea, J. M. ;
Benabarre, A. ;
Martinez-Aran, A. .
BRITISH JOURNAL OF PSYCHIATRY, 2009, 194 (03) :260-265
[8]   A randomized trial on the efficacy of group psychoeducation in the prophylaxis of recurrences in bipolar patients whose disease is in remission [J].
Colom, F ;
Vieta, E ;
Martínez-Arán, A ;
Reinares, M ;
Goikolea, JM ;
Benabarre, A ;
Torrent, C ;
Comes, M ;
Corbella, B ;
Parramon, G ;
Corominas, J .
ARCHIVES OF GENERAL PSYCHIATRY, 2003, 60 (04) :402-407
[9]  
Colom F., 2006, PSYCHOEDUCATION MANU, VFirst
[10]  
Kemp R., 1996, TREATMENT COMPLIANCE, P61