Identification of sialyl oligosaccharides including an oligosaccharide nucleotide in colostrum of an addax (Addax nasomaculatus) (Subfamily Antelopinae)

被引：6

作者：

Ganzorig, Khuukhenbaatar ^{[1
]}

Asakawa, Takuya ^{[2
]}

Sasaki, Masashi ^{[1
]}

Saito, Tadao ^{[3
]}

Suzuki, Isao ^{[2
]}

Fukuda, Kenji ^{[1
]}

Urashima, Tadasu ^{[1
]}

机构：

[1] Obihiro Univ Agr & Vet Med, Grad Sch Anim & Food Hyg, Obihiro, Hokkaido 0808555, Japan

[2] Himeji Cent Pk, Himeji, Hyogo, Japan

[3] Tohoku Univ, Grad Sch Agr, Sendai, Miyagi, Japan

来源：

ANIMAL SCIENCE JOURNAL | 2018年 / 89卷 / 01期

基金：

日本学术振兴会;

关键词：

addax colostrum; Bovidae milk oligosaccharides; milk sugar nucleotide; sialyl milk oligosaccharides; ACID-SOLUBLE NUCLEOTIDES; HUMAN-MILK;

D O I：

10.1111/asj.12899

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Mammalian milk/colostrum usually contains milk oligosaccharides along with the predominant lactose. Although milk oligosaccharides of a variety of Bovidae species including cow, sheep and goat have been characterized, those of the addax, an Antelopinae species of the Bovidae, have not as yet been clarified. In this study, several sialyl oligosaccharides were purified from a sample of addax colostrum and characterized as follows: Neu5Ac(2-8)Neu5Ac(2-3)Gal(1-4)Glc, Neu5Gc(2-8)Neu5Gc(2-3)Gal(1-4)Glc, Neu5Ac(2-3)Gal(1-4)Glc, Neu5Ac(2-6)Gal(1-4)GlcNAc, Neu5Gc(2-3)Gal(1-4)Glc, Neu5Gc(2-6)Gal(1-4)Glc, Neu5Gc(2-6)Gal(1-4)GlcNAc. In addition, an oligosaccharide nucleotide Neu5Gc(2-6)Gal(1-4)GlcNAc1-UDP was characterized. Molecular species of a variety of sialyl oligosaccharides found in milk and colostrum of these Bovidae were compared.

引用

页码：167 / 175

页数：9

共 21 条

[1] A comparative study of free oligosaccharides in the milk of domestic animals [J].

Albrecht, Simone ;

Lane, Jonathan A. ;

Marino, Karina ;

Al Busadah, Khalid A. ;

Carrington, Stephen D. ;

Hickey, Rita M. ;

Rudd, Pauline M. .

BRITISH JOURNAL OF NUTRITION, 2014, 111 (07) :1313-1328

[2] Human milk oligosaccharides: Every baby needs a sugar mama [J].

Bode, Lars .

GLYCOBIOLOGY, 2012, 22 (09) :1147-1162

[3] Sialylated Milk Oligosaccharides Promote Microbiota-Dependent Growth in Models of Infant Undernutrition [J].

Charbonneau, Mark R. ;

O'Donnell, David ;

Blanton, Laura V. ;

Totten, Sarah M. ;

Davis, Jasmine C. C. ;

Barratt, Michael J. ;

Cheng, Jiye ;

Guruge, Janaki ;

Talcott, Michael ;

Bain, James R. ;

Muehlbauer, Michael J. ;

Ilkayeva, Olga ;

Wu, Chao ;

Struckmeyer, Tedd ;

Barile, Daniela ;

Mangani, Charles ;

Jorgensen, Josh ;

Fan, Yue-mei ;

Maleta, Kenneth ;

Dewey, Kathryn G. ;

Ashorn, Per ;

Newgard, Christopher B. ;

Lebrilla, Carlito ;

Mills, David A. ;

Gordon, Jeffrey I. .

CELL, 2016, 164 (05) :859-871

[4] A COLORIMETRIC METHOD FOR THE DETERMINATION OF SUGARS [J].

DUBOIS, M ;

GILLES, K ;

HAMILTON, JK ;

REBERS, PA ;

SMITH, F .

NATURE, 1951, 168 (4265) :167-167

[5] COMPARATIVE BIOCHEMICAL STUDIES OF MILKS .2. DIALYZABLE CARBOHYDRATES [J].

JENNESS, R ;

REGEHR, EA ;

SLOAN, RE .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, 1964, 13 (04) :339-&

[6]

Jourdian G. W., 1961, Federation Proceedings. Federation of American Societies for Experimental Biology, V20, P161

[7]

JOURDIAN GW, 1971, J BIOL CHEM, V246, P430

[8] ACID-SOLUBLE NUCLEOTIDES OF MILK .4. CHEMICAL STRUCTURE OF UDP-X3 [J].

KOBATA, A .

JOURNAL OF BIOCHEMISTRY, 1966, 59 (01) :63-&

[9] ACID-SOLUBLE NUCLEOTIDES OF MILK .3. OCCURRENCE OF UDP-N-ACETYLLACTOSAMINE AND UDP-D-XYLOSE IN PIGS MILK AND COLOSTRUM [J].

KOBATA, A ;

SUZUOKIZ. .

BIOCHIMICA ET BIOPHYSICA ACTA, 1965, 107 (03) :405-&

[10] ACILD-SOUBLE NUCLEOTIDES OF MILK .2. ISOLATION AND IDENTIFICATION OF 2 NOVEL URIDINE NUCLEOTIDE OLIGOSACCHARIDE CONJUGATES FROM HUMAN MILK AND COLOSTRUM [J].

KOBATA, A .

JOURNAL OF BIOCHEMISTRY, 1963, 53 (03) :167-&

← 1 2 3 →