Efficacy of contrast medium use for neuroimaging at 3.0 T - Utility of IR-FSE compared to other T1-weighted pulse sequences

被引:16
作者
Fischbach, F [1 ]
Bruhn, H [1 ]
Pech, M [1 ]
Neumann, F [1 ]
Ricke, J [1 ]
Felix, R [1 ]
Hofmann, KT [1 ]
机构
[1] Humboldt Univ, Sch Med, Dept Radiol Charite, D-13353 Berlin, Germany
关键词
magnetic resonance imaging; ultra-high field; contrast media; blood-brain barrier disruption;
D O I
10.1097/01.rct.0000166636.85918.3d
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
As inversion-recovery (IR) technique improves T1 contrast at high field strength, signal enhancement by T1-shortening contrast media may be affected. To clarify the different enhancement properties at 3.0 T, the authors compared T1-weighted sequences. Twelve contrast-enhancing lesions were investigated by spin-echo (SE), inversion recovery fast spin-echo (IR-FSE), two-dimensional gradient-echo (2D GE), and magnetization-prepared three-dimensional gradient-echo (3D GE) sequences and evaluated by comparing signal-intensity enhancements within the lesions. In addition, signal-to-noise-ratios (SNR) and contrast-to-noise-ratios (CNR) were measured. On average, signal enhancement of the lesions amounted to 60% for SE, 57% for IR-FSE, 32% for 2D GE, and 35% for 3D GE images. CNR of gray matter versus white matter was significantly higher for IR SE and GE imaging than for genuine SE and 2D GE acquisitions (Wilcoxon test), while 2D GE imaging alone had an excellent SNR. As IR-FSE images provide an excellent CNR for gray and white matter in the brain and contrast enhancement performs almost similarly well compared with SE imaging, this technique appears to be well suited for T1-weighted neuroimaging without and with contrast enhancement at 3.0 T. However, the inherent blurring of the IR-FSE can lead to poor performance for very small lesions.
引用
收藏
页码:499 / 505
页数:7
相关论文
共 14 条
  • [1] BRANTZAWADZKI M, 1986, AM J NEURORADIOL, V7, P781
  • [2] CARR DH, 1984, LANCET, V1, P484
  • [3] BRAIN-TUMORS - MR IMAGING WITH GADOLINIUM-DTPA
    FELIX, R
    SCHORNER, W
    LANIADO, M
    NIENDORF, HP
    CLAUSSEN, C
    FIEGLER, W
    SPECK, U
    [J]. RADIOLOGY, 1985, 156 (03) : 681 - 688
  • [4] INVERSION IN THE STEADY-STATE - CONTRAST OPTIMIZATION AND REDUCED IMAGING TIME WITH FAST 3-DIMENSIONAL INVERSION-RECOVERY - PREPARED GRE PULSE SEQUENCES
    FOO, TKF
    SAWYER, AM
    FAULKNER, WH
    MILLS, DG
    [J]. RADIOLOGY, 1994, 191 (01) : 85 - 90
  • [5] HAUSTEIN J, 1992, AM J NEURORADIOL, V13, P1199
  • [6] Characterization of cerebral microangiopathy using 3 Tesla MRI: Correlation with neurological impairment and vascular risk factors
    Hund-Georgiadis, M
    Ballaschke, O
    Scheid, R
    Norris, DG
    von Cramon, DY
    [J]. JOURNAL OF MAGNETIC RESONANCE IMAGING, 2002, 15 (01) : 1 - 7
  • [7] LANIADO M, 1984, PHYSIOL CHEM PHYS, V16, P157
  • [8] Laniado M, 1986, Acta Radiol Suppl, V369, P469
  • [9] Magnetic resonance imaging contrast enhancement of brain tumors at 3 tesla versus 1.5 tesla
    Nöbauer-Huhmann, IM
    Ba-Ssalamah, A
    Mlynarik, V
    Barth, M
    Schöggl, A
    Heimberger, K
    Matula, C
    Fog, A
    Kaider, A
    Trattnig, S
    [J]. INVESTIGATIVE RADIOLOGY, 2002, 37 (03) : 114 - 119
  • [10] Field strength and dose dependence of contrast enhancement by gadolinium-based MR contrast agents
    Rinck, PA
    Muller, RN
    [J]. EUROPEAN RADIOLOGY, 1999, 9 (05) : 998 - 1004