Low-dose aspirin and breast cancer risk: results by tumour characteristics from a randomised trial

被引：39

作者：

Zhang, S. M. ^{[1
]}

Cook, N. R. ^{[1
,2
]}

Manson, J. E. ^{[1
,2
,3
]}

Lee, I-M ^{[1
,2
]}

Buring, J. E. ^{[1
,2
,4
]}

机构：

[1] Brigham & Womens Hosp, Dept Med, Div Prevent Med, Boston, MA 02215 USA

[2] Harvard Sch Publ Hlth, Dept Epidemiol, Boston, MA USA

[3] Brigham & Womens Hosp, Dept Med, Channing Lab, Boston, MA 02215 USA

[4] Harvard Univ, Sch Med, Dept Ambulatory Care & Prevent, Boston, MA USA

来源：

BRITISH JOURNAL OF CANCER | 2008年 / 98卷 / 05期

关键词：

aspirin; breast cancer; incidence;

D O I：

10.1038/sj.bjc.6604240

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The Women's Health Study trial previously reported no overall effect of low-dose aspirin (100 mg every other day) on invasive breast cancer over an average of 10 years of treatment. The present subgroup analyses further show no effects by tumour characteristics at diagnosis, suggesting that low-dose aspirin has no preventive effect on breast cancer.

引用

页码：989 / 991

页数：3

共 12 条

[1] Low-dose aspirin in the primary prevention of cancer the women's health study: A randomized controlled trial [J].

Cook, NR ;

Lee, IM ;

Gaziano, JM ;

Gordon, D ;

Ridker, PM ;

Manson, JE ;

Hennekens, CH ;

Buring, JE .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2005, 294 (01) :47-55

[2] Aspirin and breast cancer prevention - The estrogen connection [J].

DuBois, RN .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 291 (20) :2488-2489

[3] Nonsteroidal antiinflammatory drugs and breast cancer risk - The multiethnic cohort [J].

Gill, Jasmeet K. ;

Maskarinec, Gertraud ;

Wilkens, Lynne R. ;

Pike, Malcolm C. ;

Henderson, Brian E. ;

Kolonel, Laurence N. .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 2007, 166 (10) :1150-1158

[4]

Harris RE, 2003, CANCER RES, V63, P6096

[5] Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice [J].

Liu, CH ;

Chang, SH ;

Narko, K ;

Trifan, OC ;

Wu, MT ;

Smith, E ;

Haudenschild, C ;

Lane, TF ;

Hla, T .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (21) :18563-18569

[6] Nonsteroidal anti-inflammatory drug use and breast cancer risk by stage and hormone receptor status [J].

Marshall, SF ;

Bernstein, L ;

Anton-Culver, H ;

Deapen, D ;

Horn-Ross, PL ;

Mohrenweiser, H ;

Peel, D ;

Pinder, R ;

Purdie, DM ;

Reynolds, P ;

Stram, D ;

West, D ;

Wright, WE ;

Ziogas, A ;

Ross, RK .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2005, 97 (11) :805-812

[7] Association between frequent use of nonsteroidal anti-inflammatory drugs and breast cancer [J].

Rahme, E ;

Ghosn, J ;

Dasgupta, K ;

Rajan, R ;

Hudson, M .

BMC CANCER, 2005, 5 (1)

[8]

READY A, 2007, BREAST CANC RES TREA

[9]

Ristimäki A, 2002, CANCER RES, V62, P632

[10] Risk of breast cancer among users of aspirin and other antiinflammatory drugs [J].

Rodríguez, LAG ;

González-Pérez, A .

BRITISH JOURNAL OF CANCER, 2004, 91 (03) :525-529

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