Intravenous thrombolysis for acute ischaemic stroke: effective blood pressure control matters

被引：21

作者：

Tsivgoulis, Georgios ^{[1
]}

Kotsis, Vasilios ^{[2
]}

Giannopoulos, Sotirios ^{[3
]}

机构：

[1] Democritus Univ Thrace, Univ Hosp Alexandroupolis, Dept Neurol, Alexandroupolis, Greece

[2] Aristotle Univ Thessaloniki, Dept Med 3, GR-54006 Thessaloniki, Greece

[3] Univ Ioannina, Sch Med, Dept Neurol, GR-45110 Ioannina, Greece

来源：

INTERNATIONAL JOURNAL OF STROKE | 2011年 / 6卷 / 02期

关键词：

blood pressure; intracranial haemorrhage; outcome; rtPA; stroke; thrombolysis; TISSUE-PLASMINOGEN-ACTIVATOR; INTRACEREBRAL HEMORRHAGE; SAFE IMPLEMENTATION; CLINICAL-PRACTICE; URGENT THERAPY; RECANALIZATION; ASSOCIATION; PREDICTORS; GUIDELINES; EXPERIENCE;

D O I：

10.1111/j.1747-4949.2010.00570.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In this Leading opinion we summarise the observational evidence endorsing current guidelines that advocate effective blood pressure control before and during an rtPA infusion and indicate that a more active blood pressure-lowering approach immediately after intravenous thrombolysis appears to be a promising therapeutic option that should be formerly evaluated in a randomised clinical trial setting. Acute ischaemic stroke is a highly treatable neuroemergency and the efficacy of the available treatment is not only related to the speed by which it is administered but also by the effective control of modifiable adverse outcome predictors including elevated blood pressure levels.

引用

页码：125 / 127

页数：3

共 31 条

[1] Guidelines for the early management of patients with ischemic stroke - A scientific statement from the Stroke Council of the American Stroke Association [J].

Adams, HP ;

Adams, RJ ;

Brott, T ;

del Zoppo, GJ ;

Furlan, A ;

Goldstein, LB ;

Grubb, RL ;

Higashida, R ;

Kidwell, C ;

Kwiatkowski, TG ;

Marler, JR ;

Hademenos, GJ .

STROKE, 2003, 34 (04) :1056-1083

[2] Relationship of Blood Pressure, Antihypertensive Therapy, and Outcome in Ischemic Stroke Treated With Intravenous Thrombolysis Retrospective Analysis From Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register (SITS-ISTR) [J].

Ahmed, Niaz ;

Wahlgren, Nils ;

Brainin, Michael ;

Castillo, Jose ;

Ford, Gary A. ;

Kaste, Markku ;

Lees, Kennedy R. ;

Toni, Danilo .

STROKE, 2009, 40 (07) :2442-2449

[3] Intravenous tissue-type plasminogen activator for treatment of acute stroke - The standard treatment with alteplase to reverse stroke (STARS) study [J].

Albers, GW ;

Bates, VE ;

Clark, WM ;

Bell, R ;

Verro, P ;

Hamilton, SA .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2000, 283 (09) :1145-1150

[4] Thrombolysis for acute stroke in routine clinical practice [J].

Bravata, DM ;

Kim, N ;

Concato, J ;

Krumholz, HM ;

Brass, LM .

ARCHIVES OF INTERNAL MEDICINE, 2002, 162 (17) :1994-2001

[5] URGENT THERAPY FOR STROKE .1. PILOT-STUDY OF TISSUE PLASMINOGEN-ACTIVATOR ADMINISTERED WITHIN 90 MINUTES [J].

BROTT, TG ;

HALEY, EC ;

LEVY, DE ;

BARSAN, W ;

BRODERICK, J ;

SHEPPARD, GL ;

SPILKER, J ;

KONGABLE, GL ;

MASSEY, S ;

REED, R ;

MARLER, JR .

STROKE, 1992, 23 (05) :632-640

[6] Blood pressure decrease during the acute phase of ischemic stroke is associated with brain injury and poor stroke outcome [J].

Castillo, J ;

Leira, R ;

García, MM ;

Serena, J ;

Blanco, M ;

Dávalos, A .

STROKE, 2004, 35 (02) :520-526

[7] Predictors of good outcome after intravenous tPA for acute ischemic stroke [J].

Demchuk, AM ;

Tanne, D ;

Hill, MD ;

Kasner, SE ;

Hanson, S ;

Grond, M ;

Levine, SR .

NEUROLOGY, 2001, 57 (03) :474-480

[8] Guidelines for management of ischaemic stroke and transient ischaemic attack 2008 - The European Stroke Organisation (ESO) Executive Committee and the ESO Writing Committee [J].

Hacke, Werner ;

Ringleb, Peter A. ;

Bousser, Marie-Germaine ;

Ford, Gary ;

Bath, Philip ;

Brainin, Michael ;

Caso, Valeria ;

Cervera, Alvaro ;

Chamorro, Angel ;

Cordonnier, Charlotte ;

Csiba, Laszlo ;

Davalos, Antoni ;

Diener, Hans-Christoph ;

Ferro, Jose ;

Hennerici, Michael ;

Kaste, Markku ;

Langhorne, Peter ;

Lees, Kennedy ;

Leys, Didier ;

Lodder, Jan ;

Markus, Hugh S. ;

Mas, Jean-Louis ;

Mattle, Heinrich P. ;

Muir, Keith ;

Norrving, Bo ;

Obach, Victor ;

Paolucci, Stefano ;

Ringelstein, E. Bernd ;

Schellinger, Peter D. ;

Sivenius, Juhani ;

Skvortsova, Veronika ;

Sunnerhagen, Katharina Stibrant ;

Thomassen, Lars ;

Toni, Danilo ;

von Kummer, Ruediger ;

Wahlgren, Nils Gunnar ;

Walker, Marion F. ;

Wardlaw, Joanna .

CEREBROVASCULAR DISEASES, 2008, 25 (05) :457-507

[9] URGENT THERAPY FOR STROKE .2. PILOT-STUDY OF TISSUE PLASMINOGEN-ACTIVATOR ADMINISTERED 91-180 MINUTES FROM ONSET [J].

HALEY, EC ;

LEVY, DE ;

BROTT, TG ;

SHEPPARD, GL ;

WONG, MCW ;

KONGABLE, GL ;

TORNER, JC ;

MARLER, JR .

STROKE, 1992, 23 (05) :641-645

[10] Thrombolysis for acute ischemic stroke: results of the Canadian Alteplase for Stroke Effectiveness Study [J].

Hill, MD ;

Buchan, AM .

CANADIAN MEDICAL ASSOCIATION JOURNAL, 2005, 172 (10) :1307-1312

← 1 2 3 4 →