Synthesis of DNA block copolymers with extended nucleic acid segments by enzymatic ligation: cut and paste large hybrid architectures

被引：23

作者：

Ayaz, Meryem S. ^{[2
]}

Kwak, Minseok ^{[1
]}

Alemdaroglu, Fikri E. ^{[1
]}

Wang, Jie ^{[2
]}

Berger, Ruediger ^{[2
]}

Herrmann, Andreas ^{[1
]}

机构：

[1] Univ Groningen, Dept Polymer Chem, Zernike Inst Adv Mat, NL-9747 AG Groningen, Netherlands

[2] Max Planck Inst Polymer Res, D-55128 Mainz, Germany

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 08期

关键词：

POLYMERASE;

D O I：

10.1039/c0cc04746e

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Ultra-high molecular weight DNA/polymer hybrid materials were prepared employing molecular biology techniques. Nucleic acid restriction and ligation enzymes were used to generate linear DNA di- and triblock copolymers that contain up to thousands of base pairs in the DNA segments.

引用

页码：2243 / 2245

页数：3

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