Improving spatial resolution of confocal Raman microscopy by super-resolution image restoration

被引：27

作者：

Cui, Han ^{[1
]}

Zhao, Weiqian ^{[1
]}

Wang, Yun ^{[1
]}

Fan, Ying ^{[1
]}

Qiu, Lirong ^{[1
]}

Zhu, Ke ^{[2
]}

机构：

[1] Beijing Inst Technol, Sch Optoelect, Beijing Key Lab Precis Optoelect Measurement Inst, Beijing 100081, Peoples R China

[2] Chinese Acad Sci, Inst Phys, Beijing 100190, Peoples R China

来源：

OPTICS EXPRESS | 2016年 / 24卷 / 10期

基金：

中国国家自然科学基金;

关键词：

SPECTROSCOPY;

D O I：

10.1364/OE.24.010767

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

A new super-resolution image restoration confocal Raman microscopy method (SRIR-RAMAN) is proposed for improving the spatial resolution of confocal Raman microscopy. This method can recover the lost high spatial frequency of the confocal Raman microscopy by using Poisson-MAP super-resolution imaging restoration, thereby improving the spatial resolution of confocal Raman microscopy and realizing its super-resolution imaging. Simulation analyses and experimental results indicate that the spatial resolution of SRIR-RAMAN can be improved by 65% to achieve 200 nm with the same confocal Raman microscopy system. This method can provide a new tool for high spatial resolution micro-probe structure detection in physical chemistry, materials science, biomedical science and other areas. (C) 2016 Optical Society of America

引用

页码：10767 / 10776

页数：10

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