Fe-Catalyzed insertion of fluoromethylcarbenes generated from sulfonium salts into X-H bonds (X = Si, C, P)

被引：20
作者：
Duan, Yaya [1 ]
Lin, Jin-Hong [1 ]
Xiao, Ji-Chang [1 ]
Gu, Yu-Cheng [2 ]
机构：
[1] Univ Chinese Acad Sci, Shanghai Inst Organ Chem, Chinese Acad Sci, Key Lab Organofluorine Chem, 345 Lingling Rd, Shanghai 200032, Peoples R China
[2] Syngenta, Jealotts Hill Int Res Ctr, Bracknell RG42 6EY, Berks, England
来源：
ORGANIC CHEMISTRY FRONTIERS | 2017年 / 4卷 / 10期
关键词：
MORITA-BAYLIS-HILLMAN; PHOSPHINE ORGANOCATALYSTS; CARBENE INSERTION; DIFLUOROCARBENE; ACTIVATION; FUNCTIONALIZATION; FLUORINE; DIFLUOROMETHYLATION; DIAZOMETHANE; CHEMISTRY;
D O I：
10.1039/c7qo00430c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The Fe-catalyzed insertion of fluoromethylcarbenes including trifluoromethylcarbene and difluoro-methylcarbene generated in situ from sulfonium salts (Ph2S+CH2CF3-OTf and Ph2S+(CHCFH)-C-2-H-2-OTf) into X-H (X = Si, C and P) bonds is described. The insertion of both carbenes into the Si-H bond occurred smoothly, and trifluoromethylcarbene could also insert into C-H and P-H bonds.
引用
收藏
页码：1917 / 1920
页数：4
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